SCHEMBL586923

SCHEMBL586923

FC(F)(F)C1(c2cccc(I)c2)N=N1

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 1/20 0.43
GABRB3 P28472 5/20 0.39
GABRA1 P14867 4/20 0.39
GABRG2 P18507 4/20 0.39
GABRB2 P47870 2/20 0.39
KIF11 P52732 1/20 0.34
PDE4A P27815 1/20 0.32
HCAR3 P49019 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32
KDM1A O60341 2/20 0.32
SIRT2 Q8IXJ6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22587363 0.86 ADRA2A (0.49) ADRA2AGABRB3GABRA1GABRG2GABRB2
SCHEMBL3724536 0.77 ADRA2A (0.43) ADRA2AGABRB3GABRA1GABRG2GABRB2
SCHEMBL2525541 0.77 ADRA2A (0.47) ADRA2AGABRB3GABRA1GABRG2GABRB2
SCHEMBL6854538 0.77 TSHR (0.44) ADRA2AGABRB3GABRA1GABRG2GABRB2
SCHEMBL4659933 0.75 KIF11 (0.45) ADRA2AGABRB3GABRA1GABRG2GABRB2
SCHEMBL80368 0.74 KIF11 (0.43) ADRA2AGABRB3GABRA1GABRG2GABRB2
SCHEMBL2525989 0.74 ADRA2A (0.42) ADRA2AGABRB3GABRA1GABRG2GABRB2
SCHEMBL14216811 0.73 HCAR3 (0.35) HCAR3HCAR2
SCHEMBL2528314 0.73 GABRA1 (0.41) ADRA2AGABRB3GABRA1GABRG2GABRB2
SCHEMBL3727466 0.73 KDM1A (0.53) ADRA2AGABRB3GABRA1GABRG2GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100226938-A1 Cellular and viral inactivation HEALTH AND HUMAN SERVICES, GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF 2010-09-09 US claimed
US-20090297558-A1 Inactivated Influenza Virus Compositions DEPARTMENT OF HEALTH AND HUMAN SERVICES NATIONAL INSTITUTES OF HEALTH, GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE 2009-12-03 US claimed
WO-2008054481-A2 IMPROVED INACTIVATED INFLUENZA VIRUS COMPOSITIONS GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH (US) 2008-05-08 WO claimed
EP-1727894-A1 CELLULAR AND VIRAL INACTIVATION Government of the United States of America as represented by The Secretary of the Department of Health and Human Services (US) 2006-12-06 EP claimed
WO-2005093049-A1 CELLULAR AND VIRAL INACTIVATION GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2005-10-06 WO claimed
US-12629683-B2 Oligonucleotide encoded chemical libraries Plexium, Inc. (US) 2026-05-19 US disclosed
US-12577702-B2 Oligonucleotide encoded chemical libraries, related systems, devices, and methods for detecting, analyzing, quantifying, and testing biologics/genetics Plexium, Inc. (US) 2026-03-17 US disclosed
US-12297461-B2 Methods of producing and characterizing virus vaccine and virus vaccine composition GUANGZHOU REALBENEFITSPOT PHARMACEUTICAL CO., LTD. (CN) 2025-05-13 US disclosed
US-12030057-B2 Oligonucleotide encoded chemical libraries Plexium, Inc. (US) 2024-07-09 US disclosed
EP-4382183-A2 METHODS OF PRODUCING AND CHARACTERIZING VIRUS VACCINE AND VIRUS VACCINE COMPOSITION Guangzhou Realbenefitspot Pharmaceutical Co., Ltd. (CN) 2024-06-12 EP disclosed
EP-3420076-B1 METHODS OF PRODUCING AND CHARACTERIZING VIRUS VACCINE AND VIRUS VACCINE COMPOSITION GUANGZHOU REALBENEFITSPOT PHARMACEUTICAL CO LTD (CN) 2024-02-21 EP disclosed
US-20230234065-A1 OLIGONUCLEOTIDE ENCODED CHEMICAL LIBRARIES Plexium, Inc. 2023-07-27 US disclosed
US-8268602-B2 Cellular and viral inactivation THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2012-09-18 US disclosed
EP-2417251-A1 METHOD FOR PURIFYING THE RABIES VIRUS Sanofi Pasteur (FR) 2012-02-15 EP disclosed
US-20110038890-A1 Cellular And Viral Inactivation THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2011-02-17 US disclosed
WO-2010116096-A1 METHOD FOR PURIFYING THE RABIES VIRUS SANOFI PASTEUR (FR) 2010-10-14 WO disclosed
US-20100260798-A1 Method for purifying the rabies virus SANOFI PASTEUR (FR) 2010-10-14 US disclosed
US-20100226938-A1 Cellular and viral inactivation HEALTH AND HUMAN SERVICES, GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF 2010-09-09 US disclosed
US-20090297558-A1 Inactivated Influenza Virus Compositions DEPARTMENT OF HEALTH AND HUMAN SERVICES NATIONAL INSTITUTES OF HEALTH, GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE 2009-12-03 US disclosed
US-20090297558-A1 Inactivated Influenza Virus Compositions DEPARTMENT OF HEALTH AND HUMAN SERVICES NATIONAL INSTITUTES OF HEALTH, GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE 2009-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12629683-B2 Oligonucleotide encoded chemical libraries POLL, PCNA, POLM ADRA2A 4697/4885GABRB3 2039/4885GABRA1 1941/4885
US-20090297558-A1 Inactivated Influenza Virus Compositions ITPA, IDO1, IDE ADRA2A 3648/4885GABRB3 2853/4885GABRA1 2575/4885
US-20100260798-A1 Method for purifying the rabies virus NAPA, PBRM1, S100B ADRA2A 4561/4885GABRB3 40/4885GABRA1 56/4885
US-20110038890-A1 Cellular And Viral Inactivation PDIA5, HAVCR2, MAVS ADRA2A 4723/4885GABRB3 4031/4885GABRA1 3646/4885
US-20100226938-A1 Cellular and viral inactivation TP53, IFNG, POLI ADRA2A 4550/4885GABRB3 3474/4885GABRA1 2983/4885
US-12577702-B2 Oligonucleotide encoded chemical libraries, related systems, devices, and methods for detecting, analyzing, quantifying, and testing biologics/genetics RNGTT, TNFSF11, PCNA ADRA2A 4717/4885GABRB3 3010/4885GABRA1 3019/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.