Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 11/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 11/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24096257 | 0.87 | KCNN4 (0.37) | HTR1ASLC6A2ALDH1A1KMT2APOLB | |
| SCHEMBL9921644 | 0.79 | SCN8A (0.40) | HTR1ASLC6A2SLC6A4KCNN4 | |
| SCHEMBL12129077 | 0.76 | L3MBTL1 (0.47) | TAAR1HTR1ASLC6A2GAAALDH1A1 | |
| SCHEMBL19209996 | 0.76 | TAAR1 (0.41) | TAAR1HTR1ASLC6A2GAAALDH1A1 | |
| SCHEMBL28881052 | 0.75 | ERN1 (0.43) | ALDH1A1KMT2AHTTKCNN4ALOX5AP | |
| SCHEMBL9918366 | 0.75 | TSHR (0.35) | SLC6A2ALDH1A1POLBALOX15HTT | |
| SCHEMBL21601405 | 0.74 | TAAR1 (0.48) | TAAR1HTR1ASLC6A2GAAKMT2A | |
| SCHEMBL21595767 | 0.73 | KMT2A (0.42) | TAAR1HTR1ASLC6A2GAAALDH1A1 | |
| SCHEMBL1018512 | 0.71 | KDM1A (0.54) | HTR1ASLC6A2SLC6A4SLC6A3ALOX5AP | |
| SCHEMBL17607156 | 0.71 | CXCR5 (0.42) | TAAR1HTR1ASLC6A2GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120669-A1 | THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE | BOUILLOT ANNE MARIE JEANNE | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120669-A1 | THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE | SCD, SCD5, FADS2 | TAAR1 4527/4885HTR1A 3389/4885SLC6A2 3064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.