SCHEMBL19209996

SCHEMBL19209996

[Li]COc1c(F)cccc1Cl

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.41
KMT2A Q03164 2/20 0.40
HTR1A P08908 12/20 0.40
SLC6A2 P23975 12/20 0.40
GAA P10253 1/20 0.39
SLC6A4 P31645 4/20 0.38
SLC6A3 Q01959 3/20 0.37
ALDH1A1 P00352 1/20 0.36
KDM4E B2RXH2 1/20 0.35
LPAR1 Q92633 1/20 0.35
LPAR5 Q9H1C0 1/20 0.35
BACE1 P56817 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12129077 0.80 L3MBTL1 (0.47) TAAR1KMT2AHTR1ASLC6A2GAA
SCHEMBL21601405 0.78 TAAR1 (0.48) TAAR1KMT2AHTR1ASLC6A2GAA
SCHEMBL21595767 0.77 KMT2A (0.42) TAAR1KMT2AHTR1ASLC6A2GAA
SCHEMBL3728061 0.76 TAAR1 (0.38) TAAR1KMT2AHTR1ASLC6A2GAA
SCHEMBL17607156 0.76 CXCR5 (0.42) TAAR1KMT2AHTR1ASLC6A2GAA
SCHEMBL1018512 0.76 KDM1A (0.54) HTR1ASLC6A2SLC6A4SLC6A3LPAR1
SCHEMBL3759260 0.74 HTR1A (0.44) TAAR1KMT2AHTR1ASLC6A2GAA
SCHEMBL21601434 0.73 HTR1B (0.44) TAAR1KMT2AHTR1ASLC6A4ALDH1A1
SCHEMBL1703057 0.72 TAS1R3 (0.45) TAAR1KMT2AHTR1ASLC6A2GAA
Hydrochloric Acid SCHEMBL21595936 0.72 HTR1B (0.43) TAAR1HTR1ASLC6A4ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2797933-B1 METHODS OF FORMING 4-CHLORO-2-FLUORO-3-SUBSTITUTED-PHENYLBORONIC ACID PINACOL ESTERS AND METHODS OF USING THE SAME DOW AGROSCIENCES LLC (US) 2017-08-16 EP claimed