Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 11/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 11/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 10/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.35 |
| ▸ | PLD2 | O14939 | 2/20 | 0.34 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4826946 | 1.00 | OPRM1 (0.39) | OPRM1OPRK1OPRD1ADRA1AADRA1B | |
| SCHEMBL4896395 | 0.92 | OPRK1 (0.33) | OPRM1OPRK1ADRA1ACHRM2CHRM3 | |
| SCHEMBL3802612 | 0.92 | OPRK1 (0.33) | OPRM1OPRK1ADRA1ACHRM2CHRM3 | |
| SCHEMBL4784868 | 0.85 | PLD2 (0.42) | OPRM1OPRK1ADRA1ACHRM2CHRM3 | |
| SCHEMBL3398324 | 0.83 | OPRK1 (0.43) | OPRM1OPRK1ADRA1ACHRM2CHRM3 | |
| SCHEMBL3398294 | 0.83 | OPRK1 (0.43) | OPRM1OPRK1ADRA1ACHRM2CHRM3 | |
| SCHEMBL1838770 | 0.79 | OPRM1 (0.46) | OPRM1OPRK1CHRM2CHRM3BCHE | |
| SCHEMBL1841721 | 0.79 | OPRM1 (0.46) | OPRM1OPRK1CHRM2CHRM3BCHE | |
| SCHEMBL1831703 | 0.78 | OPRM1 (0.47) | OPRM1OPRK1OPRD1ADRA1ACHRM2 | |
| SCHEMBL3400375 | 0.78 | OPRM1 (0.47) | OPRM1OPRK1OPRD1ADRA1ACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155676-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | Commissariat à l'Energie Atomique (FR) | 2010-02-24 | — | — | EP | claimed |