Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3732232 | 0.92 | APP (0.43) | HRH3LMNAALDH1A1TAAR1ALOX15 | |
| SCHEMBL3728484 | 0.86 | SMN1; SMN2 (0.43) | ALDH1A1NTRK3HSD17B10MAOBNPC1 | |
| SCHEMBL3733823 | 0.76 | MKNK1 (0.44) | LMNACYP1A2MEN1NPC1RAB9A | |
| SCHEMBL3733975 | 0.75 | CA12 (0.49) | ALDH1A1TAAR1CYP1A2CYP2C19KMT2A | |
| SCHEMBL6436320 | 0.75 | CA12 (0.49) | LMNAALDH1A1MAOBKMT2A | |
| SCHEMBL1054259 | 0.75 | NTRK1 (0.42) | ALDH1A1CYP1A2CYP2C19MEN1NPC1 | |
| SCHEMBL3737684 | 0.73 | CA12 (0.53) | LMNAALDH1A1HSD17B10RAB9AKMT2A | |
| SCHEMBL20547078 | 0.73 | GABRA5 (0.50) | LMNAALDH1A1NTRK3MEN1KMT2A | |
| SCHEMBL3733770 | 0.73 | CA12 (0.42) | LMNAALDH1A1ALOX15TDP1MEN1 | |
| SCHEMBL3728433 | 0.71 | KAT2B (0.45) | ALDH1A1CYP1A2CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825132-B2 | Inhibition of FGFR3 and treatment of multiple myeloma | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2010-11-02 | — | — | US | disclosed |