Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.51 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9423475 | 0.80 | PRMT5 (0.54) | PKMALDH1A1LMNAGAAPRMT5 | |
| SCHEMBL439062 | 0.80 | PRMT5 (0.54) | PKMALDH1A1LMNAGAAPRMT5 | |
| SCHEMBL9423564 | 0.80 | PRMT5 (0.54) | PKMALDH1A1LMNAGAAPRMT5 | |
| SCHEMBL7472174 | 0.80 | PRMT5 (0.54) | PKMALDH1A1LMNAGAAPRMT5 | |
| SCHEMBL3961853 | 0.80 | PRMT5 (0.54) | PKMALDH1A1LMNAGAAPRMT5 | |
| SCHEMBL7468390 | 0.80 | PRMT5 (0.54) | PKMALDH1A1LMNAGAAPRMT5 | |
| SCHEMBL439063 | 0.80 | PRMT5 (0.54) | PKMALDH1A1LMNAGAAPRMT5 | |
| SCHEMBL3725233 | 0.80 | PRMT5 (0.54) | PKMALDH1A1LMNAGAAPRMT5 | |
| SCHEMBL450879 | 0.80 | PRMT5 (0.54) | PKMALDH1A1LMNAGAAPRMT5 | |
| SCHEMBL58865 | 0.80 | PRMT5 (0.60) | PKMALDH1A1LMNAGAAPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007408-A2 | INTERMEDIATES 2-(2-CHLORO-5-HYDROXY-4-METHYLCARBAMOYLPHENOXY)-2-METHYLPROPIONIC ACID TERT-BUTYL ESTER AND GLYCIDYL BENZENE SULFONATES OR SALTS THEREOF AND THE PROCESS FOR PREPARATION OF SAID INTERMEDIATES | ASTRAZENECA AB (SE) | 2010-01-21 | — | — | WO | claimed |
| WO-2010007408-A2 | INTERMEDIATES 2-(2-CHLORO-5-HYDROXY-4-METHYLCARBAMOYLPHENOXY)-2-METHYLPROPIONIC ACID TERT-BUTYL ESTER AND GLYCIDYL BENZENE SULFONATES OR SALTS THEREOF AND THE PROCESS FOR PREPARATION OF SAID INTERMEDIATES | ASTRAZENECA AB (SE) | 2010-01-21 | — | — | WO | disclosed |