SCHEMBL3961853

SCHEMBL3961853

O=S(=O)(OCC1CO1)c1ccc(Br)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT5 O14744 1/20 0.54
WDR77 Q9BQA1 1/20 0.54
ALDH1A1 P00352 4/20 0.50
PKM P14618 2/20 0.50
LMNA P02545 2/20 0.50
GAA P10253 1/20 0.50
CYP3A4 P08684 3/20 0.46
TSHR P16473 3/20 0.46
CYP2D6 P10635 2/20 0.46
MAPT P10636 2/20 0.46
MAPK1 P28482 2/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
PLCG1 P19174 1/20 0.41
CA2 P00918 4/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
TP53 P04637 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9423564 0.83 PRMT5 (0.54) PRMT5WDR77ALDH1A1PKMLMNA
SCHEMBL9423475 0.83 PRMT5 (0.54) PRMT5WDR77ALDH1A1PKMLMNA
SCHEMBL450879 0.83 PRMT5 (0.54) PRMT5WDR77ALDH1A1PKMLMNA
SCHEMBL439062 0.83 PRMT5 (0.54) PRMT5WDR77ALDH1A1PKMLMNA
SCHEMBL7468390 0.83 PRMT5 (0.54) PRMT5WDR77ALDH1A1PKMLMNA
SCHEMBL439063 0.83 PRMT5 (0.54) PRMT5WDR77ALDH1A1PKMLMNA
SCHEMBL3725233 0.83 PRMT5 (0.54) PRMT5WDR77ALDH1A1PKMLMNA
SCHEMBL7472174 0.83 PRMT5 (0.54) PRMT5WDR77ALDH1A1PKMLMNA
SCHEMBL58865 0.82 PRMT5 (0.60) PRMT5WDR77ALDH1A1PKMLMNA
SCHEMBL9844160 0.82 PRMT5 (0.60) PRMT5WDR77ALDH1A1PKMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1603962-B1 IMPROVEMENTS IN OR RELATING TO THERMOSETTING RESIN COMPOSITIONS HEXCEL COMPOSITES LTD (GB) 2009-02-04 EP claimed
EP-0930307-B1 PROCESS FOR THE PREPARATION OF GLYCIDYL ETHERS DAISO CO LTD (JP) 2002-12-04 EP disclosed
EP-0930291-B1 PROCESS FOR THE PREPARATION OF 3-AMINO-2-HYDROXY-1-PROPYL ETHERS DAISO CO LTD (JP) 2002-08-14 EP disclosed
US-6087512-A Process for preparation of glycidyl ether DAISO CO., LTD. (JP) 2000-07-11 US disclosed
US-6057476-A Process for the preparation of 3-amino-2-hydroxy-1-propyl ethers DAISO CO., LTD. (JP) 2000-05-02 US disclosed
EP-0930291-A1 PROCESS FOR THE PREPARATION OF 3-AMINO-2-HYDROXY-1-PROPYL ETHERS DAISO CO., LTD. (JP) 1999-07-21 EP disclosed
EP-0930307-A1 PROCESS FOR THE PREPARATION OF GLYCIDYL ETHERS DAISO CO., LTD. (JP) 1999-07-21 EP disclosed
EP-0609025-B1 Process for producing optically active epoxy alcohol derivatives ARCO CHEM TECH (US) 1996-04-17 EP disclosed
EP-0609025-A1 Process for producing optically active epoxy alcohol derivatives ARCO Chemical Technology, L.P. (US) 1994-08-03 EP disclosed