Ethylene Glycol

Ethylene Glycol

SCHEMBL3728618

CCCCOC(C)C(=O)O.OCCO

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.40
ALDH1A1 P00352 1/20 0.39
CYP4F2 P78329 1/20 0.38
CYP4A11 Q02928 1/20 0.38
ATM Q13315 1/20 0.36
CA2 P00918 1/20 0.36
MAPK1 P28482 1/20 0.36
PPARG P37231 2/20 0.36
PPARA Q07869 1/20 0.36
ACE2 Q9BYF1 1/20 0.36
HCAR2 Q8TDS4 1/20 0.36
TP53 P04637 1/20 0.36
GPR84 Q9NQS5 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Butanediol SCHEMBL3738766 0.94 SMN1; SMN2 (0.41) TSHRALDH1A1CYP4F2CYP4A11PPARG
SCHEMBL9318736 0.94 ALDH1A1 (0.43) TSHRALDH1A1CYP4F2CYP4A11ATM
SCHEMBL442956 0.94 ALDH1A1 (0.43) TSHRALDH1A1CYP4F2CYP4A11ATM
SCHEMBL9318505 0.94 ALDH1A1 (0.43) TSHRALDH1A1CYP4F2CYP4A11ATM
Hydrochloric Acid SCHEMBL9687274 0.92 ALDH1A1 (0.41) TSHRALDH1A1CYP4F2CYP4A11ATM
Di(Hydroxyethyl)Ether SCHEMBL3731192 0.91 TSHR (0.55) TSHRALDH1A1CYP4F2CYP4A11MAPK1
Tetraethylene Glycol SCHEMBL3742818 0.89 TSHR (0.53) TSHRALDH1A1CYP4F2CYP4A11MAPK1
Triethylene Glycol SCHEMBL3726980 0.89 TSHR (0.53) TSHRALDH1A1CYP4F2CYP4A11MAPK1
Propylene Glycol SCHEMBL3734585 0.89 GPR84 (0.37) ALDH1A1CYP4F2CYP4A11ATMCA2
SCHEMBL3731988 0.88 TSHR (0.47) TSHRCYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7825178-B2 Leveling agent for floor polish and aqueous floor polish composition DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2010-11-02 US disclosed
US-20070289481-A1 Leveling Agent for Floor Polish and Aqueous Floor Polish Composition DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2007-12-20 US disclosed
CN-101044221-A Leveling agent for floor polish and aqueous floor polish composition DAIHACHI CHEM IND (JP) 2007-09-26 CN disclosed