Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.58 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.58 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.53 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.51 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.51 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566135 | 0.94 | CYP4F2 (0.53) | CYP4F2CYP4A11KEAP1FFAR1PTGER1 | |
| SCHEMBL59198 | 0.91 | KEAP1 (0.65) | KEAP1FFAR1PTGER1PTGER4PTGER3 | |
| SCHEMBL8573204 | 0.87 | KEAP1 (0.56) | CYP4F2CYP4A11KEAP1FFAR1PTGER1 | |
| SCHEMBL10704357 | 0.84 | MAPT (0.61) | CYP4F2CYP4A11HDAC3MAPK1ADRA1A | |
| SCHEMBL11719124 | 0.84 | MAPT (0.61) | CYP4F2CYP4A11HDAC3MAPK1ADRA1A | |
| SCHEMBL9566173 | 0.83 | HDAC3 (0.53) | CYP4F2CYP4A11KEAP1FFAR1HDAC3 | |
| SCHEMBL29373796 | 0.83 | AKR1B1 (0.65) | KEAP1FFAR1PTGER1PTGER4PTGER3 | |
| SCHEMBL35529 | 0.83 | AKR1B1 (0.65) | KEAP1FFAR1PTGER1PTGER4PTGER3 | |
| SCHEMBL878984 | 0.83 | KEAP1 (0.56) | CYP4F2CYP4A11KEAP1FFAR1PTGER1 | |
| SCHEMBL7128255 | 0.83 | AKR1B1 (0.65) | KEAP1FFAR1PTGER1PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238107-A1 | PROCESS FOR THE MANUFACTURE OF A 6-FLUORO-1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE DERIVATIVE | Boehringer Ingelheim International GmbH (DE) | 2010-10-13 | — | — | EP | claimed |
| WO-2009092580-A1 | PROCESS FOR THE MANUFACTURE OF A 6-FLUORO-1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE DERIVATIVE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-07-30 | — | — | WO | claimed |
| US-4731126-A | HYDROXYMETHYL CARBOXYLIC ACID | THE DOW CHEMICAL COMPANY (US) | 1988-03-15 | — | — | US | claimed |
| US-11746364-B2 | Enzymatic synthesis of kavalactones and flavokavains | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2023-09-05 | — | — | US | disclosed |
| US-11739354-B2 | Enzymatic synthesis of kavalactones and flavokavains | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2023-08-29 | — | — | US | disclosed |
| WO-2008009735-A1 | PYRAZOLO (3, 4-B) PYRIDINE DERIVATIVES AS PDE4 INHIBITORS | GLAXO GROUP LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |
| CN-1931821-A | Process of resolving optical isomer of 2-hydroxmethyl-3-phenylpropionic acid | SHANGHAI INST OF MEDICINE INDU (CN) | 2007-03-21 | — | — | CN | disclosed |
| US-5280034-A | Bis-heterocyclic prostaglandin analogs | E. R. SQUIBB & SONS, INC. (US) | 1994-01-18 | — | — | US | disclosed |
| US-4731126-A | HYDROXYMETHYL CARBOXYLIC ACID | THE DOW CHEMICAL COMPANY (US) | 1988-03-15 | — | — | US | disclosed |