Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.69 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | FABP3 | P05413 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | GMNN | O75496 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL417340 | 1.00 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2NR5A2NR5A1MAPT | |
| SCHEMBL31381152 | 1.00 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2NR5A2NR5A1MAPT | |
| SCHEMBL564851 | 1.00 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2NR5A2NR5A1MAPT | |
| SCHEMBL31381151 | 0.97 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2NR5A2NR5A1MAPT | |
| SCHEMBL122604 | 0.97 | SMN1; SMN2 (0.73) | ALDH1A1SMN1; SMN2NR5A2NR5A1MAPT | |
| SCHEMBL19821335 | 0.97 | SMN1; SMN2 (0.73) | ALDH1A1SMN1; SMN2NR5A2NR5A1MAPT | |
| SCHEMBL6811206 | 0.97 | SMN1; SMN2 (0.73) | ALDH1A1SMN1; SMN2NR5A2NR5A1MAPT | |
| SCHEMBL18092159 | 0.92 | SMN1; SMN2 (0.66) | ALDH1A1SMN1; SMN2NR5A2NR5A1MAPT | |
| SCHEMBL23834444 | 0.92 | NR5A2 (0.83) | ALDH1A1SMN1; SMN2NR5A2NR5A1MAPT | |
| SCHEMBL10498201 | 0.92 | NR5A2 (0.83) | ALDH1A1SMN1; SMN2NR5A2NR5A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7811988-B2 | Lipid mixtures for synthetic surfactants | CHIESI FARMACEUTICI S.P.A. (IT) | 2010-10-12 | — | — | US | claimed |
| EP-1628634-B1 | NOVEL LIPID MIXTURES FOR SYNTHETIC SURFACTANTS | CHIESI FARMA SPA (IT) | 2009-12-23 | — | — | EP | claimed |
| US-20080045449-A1 | A lipid mixture for synthetic surfactants comprising >40% by weight of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and >10% of polyunsaturated phospholipids; treatment of surfactant deficiencies like infant respiratory distress syndrome (RDS); rheology; low surface tension; fast spreading | CHIESI FARMACEUTICI S.P.A. (IT) | 2008-02-21 | — | — | US | claimed |
| EP-3727418-B1 | SURFACTANT FORMULATIONS FOR INHALATION | MERZ PHARMACEUTICALS LLC (US) | 2026-04-08 | — | — | EP | disclosed |
| EP-3474832-B1 | SURFACTANT FORMULATIONS FOR INHALATION | MERZ PHARMACEUTICALS LLC (US) | 2026-03-18 | — | — | EP | disclosed |
| US-20250288516-A1 | Surfactant Formulations for Inhalation | MERZ PHARMACEUTICALS LLC (US) | 2025-09-18 | — | — | US | disclosed |
| US-20250262150-A1 | Surfactant Formulations for Inhalation | MERZ PHARMACEUTICALS LLC (US) | 2025-08-21 | — | — | US | disclosed |
| US-20240016823-A1 | SURFACTANT FORMULATIONS FOR INHALATION | MERZ PHARMACEUTICALS, LLC | 2024-01-18 | — | — | US | disclosed |
| US-20210386664-A1 | Surfactant Formulations for Inhalation | MERZ PHARMACEUTICALS, LLC | 2021-12-16 | — | — | US | disclosed |
| US-20210169794-A1 | Surfactant Formulations for Inhalation | MERZ PHARMACEUTICALS, LLC | 2021-06-10 | — | — | US | disclosed |
| EP-3474832-A1 | SURFACTANT FORMULATIONS FOR INHALATION | Civitas Therapeutics, Inc. (US) | 2019-05-01 | — | — | EP | disclosed |
| WO-2017223502-A1 | SURFACTANT FORMULATIONS FOR INHALATION | CIVITAS THERAPEUTICS, INC. (US) | 2017-12-28 | — | — | WO | disclosed |
| US-7811988-B2 | Lipid mixtures for synthetic surfactants | CHIESI FARMACEUTICI S.P.A. (IT) | 2010-10-12 | — | — | US | disclosed |
| EP-1628634-B1 | NOVEL LIPID MIXTURES FOR SYNTHETIC SURFACTANTS | CHIESI FARMA SPA (IT) | 2009-12-23 | — | — | EP | disclosed |
| US-20080045449-A1 | A lipid mixture for synthetic surfactants comprising >40% by weight of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and >10% of polyunsaturated phospholipids; treatment of surfactant deficiencies like infant respiratory distress syndrome (RDS); rheology; low surface tension; fast spreading | CHIESI FARMACEUTICI S.P.A. (IT) | 2008-02-21 | — | — | US | disclosed |
| EP-1628634-A1 | NOVEL LIPID MIXTURES FOR SYNTHETIC SURFACTANTS | CHIESI FARMACEUTICI S.p.A. (IT) | 2006-03-01 | — | — | EP | disclosed |
| WO-2004105726-A1 | NOVEL LIPID MIXTURES FOR SYNTHETIC SURFACTANTS | CHIESI FARMACEUTICI S.P.A. (IT) | 2004-12-09 | — | — | WO | disclosed |
| EP-1481665-A1 | Novel lipid mixtures for synthetic surfactants | CHIESI FARMACEUTICI S.p.A. (IT) | 2004-12-01 | — | — | EP | disclosed |