Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.73 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | FABP3 | P05413 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | GMNN | O75496 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL122604 | 1.00 | SMN1; SMN2 (0.73) | SMN1; SMN2NR5A2NR5A1MAPTALDH1A1 | |
| SCHEMBL6811206 | 1.00 | SMN1; SMN2 (0.73) | SMN1; SMN2NR5A2NR5A1MAPTALDH1A1 | |
| SCHEMBL3728919 | 0.97 | ALDH1A1 (0.73) | SMN1; SMN2NR5A2NR5A1MAPTALDH1A1 | |
| SCHEMBL417340 | 0.97 | ALDH1A1 (0.73) | SMN1; SMN2NR5A2NR5A1MAPTALDH1A1 | |
| SCHEMBL564851 | 0.97 | ALDH1A1 (0.73) | SMN1; SMN2NR5A2NR5A1MAPTALDH1A1 | |
| SCHEMBL18092159 | 0.95 | SMN1; SMN2 (0.66) | SMN1; SMN2NR5A2NR5A1MAPTALDH1A1 | |
| SCHEMBL19092850 | 0.94 | SMN1; SMN2 (0.82) | SMN1; SMN2NR5A2NR5A1MAPTALDH1A1 | |
| SCHEMBL22479276 | 0.94 | SMN1; SMN2 (0.82) | SMN1; SMN2NR5A2NR5A1MAPTALDH1A1 | |
| SCHEMBL11996375 | 0.94 | SMN1; SMN2 (0.82) | SMN1; SMN2NR5A2NR5A1MAPTALDH1A1 | |
| SCHEMBL25354838 | 0.91 | SMN1; SMN2 (0.88) | SMN1; SMN2NR5A2NR5A1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230130155-A1 | MRNAS ENCODING METABOLIC REPROGRAMMING POLYPEPTIDES AND USES THEREOF | ARES CAPITAL CORPORATION, AS AGENT | 2023-04-27 | — | — | US | disclosed |
| US-20180028664-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS | MODERNATX, INC. (US) | 2018-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180028664-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS | HDLBP, APOB, TSG101 | SMN1; SMN2 209/4885NR5A2 4295/4885NR5A1 4197/4885 |
| US-20230130155-A1 | MRNAS ENCODING METABOLIC REPROGRAMMING POLYPEPTIDES AND USES THEREOF | HMOX1, CD209, HMOX2 | SMN1; SMN2 3558/4885NR5A2 1617/4885NR5A1 2138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.