Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.66 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | FABP3 | P05413 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | GMNN | O75496 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19821335 | 0.95 | SMN1; SMN2 (0.73) | SMN1; SMN2NR5A2NR5A1MAPTALDH1A1 | |
| SCHEMBL122604 | 0.95 | SMN1; SMN2 (0.73) | SMN1; SMN2NR5A2NR5A1MAPTALDH1A1 | |
| SCHEMBL6811206 | 0.95 | SMN1; SMN2 (0.73) | SMN1; SMN2NR5A2NR5A1MAPTALDH1A1 | |
| SCHEMBL18037179 | 0.92 | SMN1; SMN2 (0.79) | SMN1; SMN2NR5A2NR5A1MAPTALDH1A1 | |
| SCHEMBL3130105 | 0.92 | SMN1; SMN2 (0.79) | SMN1; SMN2NR5A2NR5A1MAPTALDH1A1 | |
| SCHEMBL564851 | 0.92 | ALDH1A1 (0.73) | SMN1; SMN2NR5A2NR5A1MAPTALDH1A1 | |
| SCHEMBL417340 | 0.92 | ALDH1A1 (0.73) | SMN1; SMN2NR5A2NR5A1MAPTALDH1A1 | |
| SCHEMBL3728919 | 0.92 | ALDH1A1 (0.73) | SMN1; SMN2NR5A2NR5A1MAPTALDH1A1 | |
| SCHEMBL11996375 | 0.89 | SMN1; SMN2 (0.82) | SMN1; SMN2NR5A2NR5A1MAPTALDH1A1 | |
| SCHEMBL22479276 | 0.89 | SMN1; SMN2 (0.82) | SMN1; SMN2NR5A2NR5A1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844078-B1 | PHARMACEUTICAL COMPOSITIONS WITH ENHANCED PERFORMANCE | BEND RES INC (US) | 2016-09-28 | — | — | EP | disclosed |