Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | FABP7 | O15540 | 1/20 | 0.43 |
| ▸ | FABP3 | P05413 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423160 | 0.82 | KAT6A (0.38) | L3MBTL1TDP1MAPK1LMNABACE1 | |
| SCHEMBL4974891 | 0.82 | PTGDR2 (0.60) | L3MBTL1TDP1ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL28047804 | 0.81 | MAPK1 (0.43) | L3MBTL1TDP1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3728321 | 0.81 | KDM4E (0.58) | L3MBTL1TDP1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8423155 | 0.80 | BACE1 (0.42) | L3MBTL1TDP1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9180717 | 0.80 | LMNA (0.55) | L3MBTL1TDP1KDM4EALDH1A1SMN1; SMN2 | |
| Bicarbonate SCHEMBL9330276 | 0.79 | KDM4E (0.56) | L3MBTL1TDP1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5967718 | 0.79 | PTGDR2 (0.57) | ALDH1A1LMNABACE1TSHRRAB9A | |
| SCHEMBL28008237 | 0.78 | KDM4E (0.46) | L3MBTL1TDP1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL23358801 | 0.77 | HTT (0.45) | L3MBTL1TDP1KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120669-A1 | THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE | BOUILLOT ANNE MARIE JEANNE | 2010-05-13 | — | — | US | disclosed |
| CN-101490001-A | Substituted phenylacetic acids as DP-2 antagonists | ICOS CORP (US) | 2009-07-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120669-A1 | THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE | SCD, SCD5, FADS2 | L3MBTL1 3539/4885TDP1 1661/4885KDM4E 1233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.