Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423158 | 0.84 | BACE1 (0.55) | BACE1TDP1KDM4EALDH1A1ADORA3 | |
| SCHEMBL8423160 | 0.81 | KAT6A (0.38) | BACE1L3MBTL1TDP1ADORA3ADORA2A | |
| SCHEMBL3729774 | 0.80 | L3MBTL1 (0.47) | BACE1L3MBTL1TDP1KDM4EALDH1A1 | |
| SCHEMBL7194362 | 0.75 | CYP1A1 (0.50) | L3MBTL1TDP1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8424973 | 0.74 | TSHR (0.42) | TDP1ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL21540608 | 0.74 | ALDH1A1 (0.46) | EGFRKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4974891 | 0.74 | PTGDR2 (0.60) | BACE1PTGDR2L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL5967718 | 0.72 | PTGDR2 (0.57) | BACE1PTGDR2ALDH1A1ADORA3ADORA2A | |
| SCHEMBL11492331 | 0.69 | KDM4E (0.54) | EGFRTDP1KDM4EALDH1A1LMNA | |
| SCHEMBL5967713 | 0.69 | PTGDR2 (0.62) | PTGDR2L3MBTL1ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5985853-A | β-methoxy acrylic acid derivatives, method for preparing same, and use of said derivatives as pesticides | HOECHST MARION ROUSSEL (FR) | 1999-11-16 | — | — | US | disclosed |