Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | PDE2A | O00408 | 1/20 | 0.50 |
| ▸ | PDE5A | O76074 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.50 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.50 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3721362 | 0.76 | SMN1; SMN2 (0.49) | ALDH1A1PDE2APDE5ACYP3A4ALOX15 | |
| SCHEMBL8848558 | 0.76 | ALDH1A1 (0.70) | ALDH1A1PDE2APDE5ACYP3A4ALOX15 | |
| SCHEMBL27518366 | 0.75 | L3MBTL1 (0.53) | ALDH1A1PDE2APDE5ACYP3A4ALOX15 | |
| SCHEMBL29886712 | 0.75 | NPBWR1 (0.73) | ALDH1A1NFKB1L3MBTL1NPBWR1MMP2 | |
| SCHEMBL3836178 | 0.75 | NPBWR1 (0.73) | ALDH1A1NFKB1L3MBTL1NPBWR1MMP2 | |
| SCHEMBL7366348 | 0.74 | KMT2A (0.50) | ALDH1A1NFKB1L3MBTL1NPBWR1MMP2 | |
| SCHEMBL22494203 | 0.72 | L3MBTL1 (0.72) | ALDH1A1L3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8124230 | 0.71 | ALDH1A1 (0.52) | ALDH1A1PDE2APDE5ACYP3A4ALOX15 | |
| SCHEMBL6756159 | 0.71 | L3MBTL1 (0.57) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL8130626 | 0.71 | ALDH1A1 (0.46) | ALDH1A1PDE2APDE5ACYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127246-A2 | HNF4 MODULATORS AND METHODS OF USE | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-11-04 | — | — | WO | disclosed |