SCHEMBL3730178

SCHEMBL3730178

NC(=O)c1cccc2c1C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 10/20 0.59
MAPT P10636 3/20 0.59
HPGD P15428 2/20 0.59
MEN1 O00255 2/20 0.59
HTT P42858 2/20 0.59
KMT2A Q03164 2/20 0.59
CYP2C19 P33261 1/20 0.59
RECQL P46063 1/20 0.59
BLM P54132 1/20 0.59
SMAD3 P84022 1/20 0.59
PRMT1 Q99873 1/20 0.59
ACE2 Q9BYF1 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
ALDH1A1 P00352 2/20 0.56
ALOX12 P18054 2/20 0.56
CYP2C9 P11712 1/20 0.56
ALOX15 P16050 1/20 0.56
BRCA1 P38398 1/20 0.56
HSD17B10 Q99714 1/20 0.56
LMNA P02545 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10841402 0.89 FTO (0.57) FTOMAPTHPGDMEN1HTT
SCHEMBL20832 0.89 ALDH1A1 (0.60) FTOMAPTHPGDMEN1HTT
SCHEMBL2407192 0.88 FTO (0.59) FTOMAPTHPGDMEN1HTT
SCHEMBL9427960 0.88 FTO (0.59) FTOMAPTHPGDMEN1HTT
SCHEMBL2394440 0.87 HPGD (0.47) FTOMAPTHPGDMEN1HTT
SCHEMBL15902813 0.87 FTO (0.55) FTOMAPTHPGDMEN1HTT
SCHEMBL312455 0.87 FTO (0.55) FTOMAPTHPGDMEN1HTT
SCHEMBL4416360 0.86 FTO (0.57) FTOMAPTHPGDMEN1HTT
SCHEMBL6850491 0.85 FTO (0.60) FTOMAPTHPGDMEN1HTT
SCHEMBL635657 0.84 ALDH1A1 (0.51) FTOMAPTHPGDMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117120101-A Antimicrobial substrate 柏克夏公司 2023-11-24 CN claimed
CN-109983135-A Epidermal growth factor receptor detection in Gene Mutation composition and kit comprising it 建喾立嗣股份公司 2019-07-05 CN claimed
CN-102994072-A Fluorescent probe for detecting hypochlorite aions, and preparation method thereof UNIV DONGHUA 2013-03-27 CN claimed
EP-0873126-A4 LABELED VITAMIN D COMPOUNDS AND THE USE THEREOF A AND D ASSAY INC (US) 2000-04-19 EP claimed
EP-0873126-A1 LABELED VITAMIN D COMPOUNDS AND THE USE THEREOF A and D Assay, Incorporated (US) 1998-10-28 EP claimed
WO-1997024127-A1 LABELED VITAMIN D COMPOUNDS AND THE USE THEREOF A AND D ASSAY, INCORPORATED (US) 1997-07-10 WO claimed
JP-55161801-A None JP disclosed
CN-111699268-B Multiplex labelling of molecules by sequential hybridization encoding barcodes with rapid switching and re-hybridization of probes 加州理工学院 2024-04-26 CN disclosed
CN-117630372-A Immunodetection sample transfer kit and method thereof 上海思路迪生物医学科技有限公司 2024-03-01 CN disclosed
CN-117630373-A Kit and method for realizing fluorescent compound transfer printing and immunofluorescence enhancement 上海思路迪生物医学科技有限公司 2024-03-01 CN disclosed
CN-117630371-A Multiplex immunodetection sample transfer kit and method 上海思路迪生物医学科技有限公司 2024-03-01 CN disclosed
CN-117460837-A Linkage amplification with exponential radiance tether 加州理工学院 2024-01-26 CN disclosed
CN-113189070-B Nano probe, preparation method and application thereof, and detection system for miRNAs of circulating tumor cells 香港理工大学 2024-01-16 CN disclosed
WO-1997039326-A2 IN VITRO FLUORESCENCE POLARIZATION ASSAY ARIAD PHARMACEUTICALS, INC. (US) 1997-10-23 WO disclosed
EP-0457213-B1 Barbiturate assay, tracers, immunogens, antibodies and kit ABBOTT LAB (US) 1997-07-23 EP disclosed
WO-1997024127-A1 LABELED VITAMIN D COMPOUNDS AND THE USE THEREOF A AND D ASSAY, INCORPORATED (US) 1997-07-10 WO disclosed
EP-0473984-A1 1,2-Dioxetane compounds as chemiluminescent labels for organic and biological molecules THE BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) 1992-03-11 EP disclosed
EP-0457213-A2 Barbiturate assay, tracers, immunogens, antibodies and kit ABBOTT LABORATORIES (US) 1991-11-21 EP disclosed
EP-0373508-A2 Barbiturate assay, tracers, immunogens and antibodies ABBOTT LABORATORIES (US) 1990-06-20 EP disclosed
JP-S55161801-A FLUORESCENCE-LABELED ACID MUCOPOLYSACCHARIDE AND PREPARATION THEREOF SEIKAGAKU KOGYO CO LTD 1980-12-16 JP disclosed