SCHEMBL2394440

SCHEMBL2394440

NC(=O)c1cccc2c1C(=O)OC21c2ccc(O)cc2Oc2cc(OCC(=O)O)ccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.47
ALDH1A1 P00352 3/20 0.47
HSD17B10 Q99714 2/20 0.47
CYP2C9 P11712 1/20 0.47
ALOX15 P16050 1/20 0.47
ALOX12 P18054 1/20 0.47
BRCA1 P38398 1/20 0.47
FTO Q9C0B1 8/20 0.46
MEN1 O00255 2/20 0.46
MAPT P10636 2/20 0.46
HTT P42858 2/20 0.46
KMT2A Q03164 2/20 0.46
CYP2C19 P33261 1/20 0.46
RECQL P46063 1/20 0.46
BLM P54132 1/20 0.46
SMAD3 P84022 1/20 0.46
PRMT1 Q99873 1/20 0.46
ACE2 Q9BYF1 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CYP3A4 P08684 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3730178 0.87 FTO (0.59) HPGDALDH1A1HSD17B10CYP2C9ALOX15
SCHEMBL2371477 0.82 FTO (0.70) HPGDALDH1A1HSD17B10CYP2C9ALOX15
SCHEMBL5697654 0.79 HPGD (0.51) HPGDALDH1A1HSD17B10CYP2C9ALOX15
SCHEMBL20832 0.79 ALDH1A1 (0.60) HPGDALDH1A1HSD17B10CYP2C9ALOX15
SCHEMBL2371404 0.78 HPGD (0.52) HPGDALDH1A1HSD17B10CYP2C9ALOX15
SCHEMBL6652238 0.78 HPGD (0.47) HPGDALDH1A1HSD17B10CYP2C9ALOX15
SCHEMBL991486 0.78 MAPT (0.61) HPGDALDH1A1HSD17B10CYP2C9ALOX15
SCHEMBL15902813 0.78 FTO (0.55) HPGDALDH1A1HSD17B10CYP2C9ALOX15
SCHEMBL312455 0.78 FTO (0.55) HPGDALDH1A1HSD17B10CYP2C9ALOX15
SCHEMBL9871326 0.77 FTO (0.56) HPGDALDH1A1HSD17B10CYP2C9ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12105092-B2 Molecularly imprinted particles GEORGE MASON UNIVERSITY (US) 2024-10-01 US claimed
US-12558448-B2 Immobilized pH indicator for biological indicator growth indication SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-02-24 US disclosed
US-12228555-B2 Self-contained biological indicator SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-02-18 US disclosed
US-12105092-B2 Molecularly imprinted particles GEORGE MASON UNIVERSITY (US) 2024-10-01 US disclosed
US-20230313261-A1 Biological Indicator Comprising Genetically-Modified Test Microorganism SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2023-10-05 US disclosed
US-20230193347-A1 Biological Indicator with Test Microorganisms Enveloped by Wax Composition SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2023-06-22 US disclosed
US-20230110772-A1 Immobilized pH Indicator for Biological Indicator Growth Indication SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2023-04-13 US disclosed
US-20230047207-A1 Self-Contained Biological Indicator with Salt Compound SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2023-02-16 US disclosed
US-20210311002-A1 SELF-CONTAINED BIOLOGICAL INDICATOR 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-10-07 US disclosed
WO-2021148909-A1 SELF-CONTAINED BIOLOGICAL INDICATOR WITH SALT COMPOUND 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-07-29 WO disclosed
US-20200385776-A1 COMPOSITIONS AND METHODS TO DETECT MICROORGNAISMS SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2020-12-10 US disclosed
US-20200363421-A1 MOLECULARLY IMPRINTED PARTICLES GEORGE MASON UNIVERSITY (US) 2020-11-19 US disclosed
US-20160008783-A1 PHOTOCATALYTIC DEGRADATION OF SUGAR EMPIRE TECHNOLOGY DEVELOPMENT LLC 2016-01-14 US disclosed
US-20140162309-A1 Arsenical Fluorescent Agents and Assays SRI INTERNATIONAL (US) 2014-06-12 US disclosed
US-8664009-B2 Arsenical fluorescent agents and assays SRI INTERNATIONAL (US) 2014-03-04 US disclosed
US-20110229929-A1 Arsenical Fluorescent Agents and Assays SRI INTERNATIONAL 2011-09-22 US disclosed
US-20100047859-A1 SILICA-BASED FLUORESCENT NANOPARTICLES SNU R&DB FOUNDATION (KR) 2010-02-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12558448-B2 Immobilized pH indicator for biological indicator growth indication ALPG, GUSB, HAO2 HPGD 740/4885ALDH1A1 291/4885HSD17B10 98/4885
US-20110229929-A1 Arsenical Fluorescent Agents and Assays AS3MT, ANXA5, ARSA HPGD 3250/4885ALDH1A1 77/4885HSD17B10 3312/4885
US-20100047859-A1 SILICA-BASED FLUORESCENT NANOPARTICLES NOXO1, NOX3, SOS1 HPGD 3258/4885ALDH1A1 1247/4885HSD17B10 2638/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.