⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8734085 | 0.86 | HDAC3 (0.40) | — | |
| SCHEMBL2678727 | 0.83 | HDAC3 (0.45) | — | |
| SCHEMBL8108657 | 0.79 | — | — | |
| SCHEMBL10866810 | 0.79 | HDAC3 (0.41) | — | |
| SCHEMBL5049817 | 0.79 | FAAH (0.47) | — | |
| SCHEMBL2386783 | 0.76 | — | — | |
| SCHEMBL7135125 | 0.74 | — | — | |
| SCHEMBL16853223 | 0.74 | ALDH1A1 (0.48) | — | |
| SCHEMBL16853220 | 0.74 | ALDH1A1 (0.55) | — | |
| SCHEMBL7707873 | 0.73 | TSHR (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8344177-B2 | Albumin binding molecules and uses thereof | PHILOCHEM AG (CH) | 2013-01-01 | — | — | US | claimed |
| US-20100172844-A1 | ALBUMIN BINDING MOLECULES AND USES THEREOF | PHILOCHEM AG (CH) | 2010-07-08 | — | — | US | claimed |
| EP-2094647-A2 | ALBUMIN BINDING MOLECULES AND USES THEREOF | Philochem AG (CH) | 2009-09-02 | — | — | EP | claimed |
| WO-2008053360-A2 | ALBUMIN BINDING MOLECULES AND USES THEREOF | PHILOCHEM AG (CH) | 2008-05-08 | — | — | WO | claimed |
| US-8344177-B2 | Albumin binding molecules and uses thereof | PHILOCHEM AG (CH) | 2013-01-01 | — | — | US | disclosed |
| US-20100172844-A1 | ALBUMIN BINDING MOLECULES AND USES THEREOF | PHILOCHEM AG (CH) | 2010-07-08 | — | — | US | disclosed |
| EP-2111237-A2 | FIBRIN-BINDING PEPTIDES AND CONJUGATES THEREOF | BRACCO IMAGING S.p.A. (IT) | 2009-10-28 | — | — | EP | disclosed |
| EP-2094647-A2 | ALBUMIN BINDING MOLECULES AND USES THEREOF | Philochem AG (CH) | 2009-09-02 | — | — | EP | disclosed |
| EP-1778299-A4 | METHODS FOR PREPARING MULTIVALENT CONSTRUCTS FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS | BRACCO INT BV (NL) | 2009-08-26 | — | — | EP | disclosed |
| WO-2008073458-A2 | FIBRIN-BINDING PEPTIDES AND CONJUGATES THEREOF | BRACCO IMAGING S.P.A. (IT) | 2008-06-19 | — | — | WO | disclosed |
| WO-2008053360-A2 | ALBUMIN BINDING MOLECULES AND USES THEREOF | PHILOCHEM AG (CH) | 2008-05-08 | — | — | WO | disclosed |
| EP-1778299-A2 | METHODS FOR PREPARING MULTIVALENT CONSTRUCTS FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS | BRACCO INTERNATIONAL B.V. (NL) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006096207-A2 | METHODS FOR PREPARING MULTIVALENT CONSTRUCTS FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS | BRACCO INTERNATIONAL B.V. (NL) | 2006-09-14 | — | — | WO | disclosed |