⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3265662 | 0.80 | MEN1 (0.47) | — | |
| SCHEMBL6360689 | 0.79 | — | — | |
| SCHEMBL19866578 | 0.79 | — | — | |
| SCHEMBL12799428 | 0.79 | MEN1 (0.78) | — | |
| SCHEMBL293808 | 0.77 | — | — | |
| SCHEMBL3730615 | 0.76 | — | — | |
| SCHEMBL24805490 | 0.76 | MEN1 (0.52) | — | |
| SCHEMBL1117284 | 0.76 | FAAH (0.62) | — | |
| SCHEMBL293766 | 0.75 | — | — | |
| SCHEMBL10101148 | 0.74 | MEN1 (0.89) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8017611-B2 | Pyridine and pyrazine derivatives -083 | ASTRAZENECA AB (SE) | 2011-09-13 | — | — | US | disclosed |
| EP-2215085-B1 | PYRIDINE AND PYRAZINE DERIVATIVES USEFUL IN THE TREATMENT OF CELL PROLIFERATIVE DISORDERS | ASTRAZENECA AB (SE) | 2011-09-07 | — | — | EP | disclosed |
| EP-2215085-A2 | PYRIDINE AND PYRAZINE DERIVATIVES USEFUL IN THE TREATMENT OF CELL PROLIFERATIVE DISORDERS | AstraZeneca AB (SE) | 2010-08-11 | — | — | EP | disclosed |
| US-7666906-B2 | β-Benzyloxyaspartate derivatives with amino group on benzene ring | SUNTORY HOLDINGS LIMITED (JP) | 2010-02-23 | — | — | US | disclosed |
| US-20090118305-A1 | PYRIDINE AND PYRAZINE DERIVATIVES - 083 | ASTRAZENECA AB (SE) | 2009-05-07 | — | — | US | disclosed |
| WO-2009053737-A2 | PYRIDINE AND PYRAZINE DERIVATIVES USEFUL IN THE TREATMENT OF CELL PROLIFERATIVE DISORDERS | ASTRAZENECA AB (SE) | 2009-04-30 | — | — | WO | disclosed |
| US-20070238783-A1 | Beta-benzyloxyaspartate derivatives with amino group on benzene ring | SUNTORY HOLDINGS LIMITED (JP) | 2007-10-11 | — | — | US | disclosed |
| US-7247652-B2 | β-benzyloxyaspartate derivatives with amino group on benzene ring | SUNTORY LIMITED (JP) | 2007-07-24 | — | — | US | disclosed |
| US-20040242652-A1 | Beta benzyloxyaspartate derivatives with amino group on benzene ring | SUNTORY HOLDINGS LTD. (JP) | 2004-12-02 | — | — | US | disclosed |
| EP-1397370-A1 | B-BENZYLOXYASPARTATE DERIVATIVES WITH AMINO GROUP ON BENZENE RING | SUNTORY LIMITED (JP) | 2004-03-17 | — | — | EP | disclosed |
| WO-1996000410-A1 | PHTHALIMIDE BLOCKED POST-PROCESSING STABILIZERS FOR PHOTOTHERMOGRAPHY | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-01-04 | — | — | WO | disclosed |
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| US-5439790-A | Phthalimide blocked post-processing stabilizers for photothermography | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-08-08 | — | — | US | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |
| EP-0628862-A1 | Speed enhancers and stabilizers for photothermography | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-12-14 | — | — | EP | disclosed |
| EP-0627659-A1 | Stabilizers for photothermographic materials with nitrile blocking groups | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-12-07 | — | — | EP | disclosed |
| US-5300420-A | Resistant to thermal release during shelf aging | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-04-05 | — | — | US | disclosed |
| US-5298390-A | Heterocyclic sulfides, sulfoxides and sulfones, post-processing stabilization of unreacted silver halide | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-03-29 | — | — | US | disclosed |
| US-5194623-A | AZLACTONE BASED PHOTOGRAPHIC REAGENTS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-03-16 | — | — | US | disclosed |
| EP-0473457-A2 | Azlactone based photographic reagents | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-03-04 | — | — | EP | disclosed |