Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3667568 | 0.90 | MGLL (0.42) | MGLLPTGDR2S1PR1KDM4EABHD6 | |
| SCHEMBL3666383 | 0.89 | S1PR1 (0.43) | THRATHRBPTGDR2S1PR1KDM4E | |
| SCHEMBL3670884 | 0.87 | PTGDR2 (0.44) | THRATHRBPTGDR2S1PR1KDM4E | |
| SCHEMBL1948807 | 0.85 | PTGDR2 (0.59) | PTGDR2LTB4R2 | |
| SCHEMBL3665828 | 0.85 | FSHR (0.38) | THRATHRBPTGDR2S1PR1KDM4E | |
| SCHEMBL3666210 | 0.83 | FSHR (0.40) | THRATHRBPTGDR2S1PR1KDM4E | |
| SCHEMBL3672481 | 0.82 | MTOR (0.43) | THRATHRBS1PR1LTB4R2PDK1 | |
| SCHEMBL3666876 | 0.82 | ABHD6 (0.54) | MGLLTHRATHRBPTGDR2KDM4E | |
| SCHEMBL3731306 | 0.82 | CTSA (0.39) | THRATHRBPTGDR2S1PR1KDM4E | |
| SCHEMBL3671611 | 0.81 | PDK1 (0.54) | PDK1MEN1KMT2ATACR1HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240434-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | Ligand Pharmaceuticals Inc. (US) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009089192-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | LIGAND PHARMACEUTICALS INC. (US) | 2009-07-16 | — | — | WO | disclosed |