Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3728802 | 0.96 | TRIM24 (0.32) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL3733062 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL3734780 | 0.80 | — | — | |
| SCHEMBL3738425 | 0.77 | PTGS2 (0.37) | ALDH1A1 | |
| Bromide SCHEMBL3742335 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL3735206 | 0.72 | TRIM24 (0.32) | TRIM24TRIM33ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3739947 | 0.70 | TRIM24 (0.36) | TRIM24TRIM33ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3731540 | 0.69 | — | — | |
| Bromide SCHEMBL3742530 | 0.67 | TRIM24 (0.32) | TRIM24TRIM33ALDH1A1 | |
| Bromide SCHEMBL3729280 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1900393-B1 | Hydrogen peroxide activation with diones and imidazoles | HENKEL AG & CO KGAA (DE) | 2018-02-28 | — | — | EP | disclosed |
| EP-1862198-B1 | Brightening and/or dyeing agent with urea derivatives | HENKEL AG & CO KGAA (DE) | 2017-04-05 | — | — | EP | disclosed |
| EP-2026754-B1 | LIGHTENING AND/OR COLOURING AGENT COMPRISING CYCLIC UREA DERIVATIVES | HENKEL AG & CO KGAA (DE) | 2015-09-30 | — | — | EP | disclosed |
| EP-2012742-B1 | BLEACHING AND/OR COLOURING AGENTS CONTAINING PIPERIDONES | HENKEL AG & CO KGAA (DE) | 2014-03-19 | — | — | EP | disclosed |
| US-20100278767-A1 | Lightening Agents and/or Dyes that Contain Aldehyde(s) | HENKEL AG & CO. KGAA (DE) | 2010-11-04 | — | — | US | disclosed |
| EP-1905418-A2 | Hydrogen peroxide activation with N-heterocycles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2008-04-02 | — | — | EP | disclosed |
| EP-1900393-A2 | Hydrogen peroxide activation with diones | Henkel Kommanditgesellschaft auf Aktien (DE) | 2008-03-19 | — | — | EP | disclosed |
| EP-1900355-A2 | Bleaching and/or dyeing agent with heterocyclic aldehydes | Henkel Kommanditgesellschaft auf Aktien (DE) | 2008-03-19 | — | — | EP | disclosed |
| EP-1891927-A2 | Hydrogen peroxide activation with methanol (hetero)aromatic compounds | Henkel Kommanditgesellschaft auf Aktien (DE) | 2008-02-27 | — | — | EP | disclosed |
| EP-1892013-A2 | Hydrogen peroxide activation with nonionic compounds | Henkel Kommanditgesellschaft auf Aktien (DE) | 2008-02-27 | — | — | EP | disclosed |
| EP-1882470-A2 | Hydrogen peroxide activation with betaines and/or aminoxides | Henkel Kommanditgesellschaft auf Aktien (DE) | 2008-01-30 | — | — | EP | disclosed |
| EP-1882495-A2 | Hydrogen peroxide activation with anionic tensides | Henkel Kommanditgesellschaft auf Aktien (DE) | 2008-01-30 | — | — | EP | disclosed |
| EP-1862198-A2 | Brightening and/or dyeing agent with urea derivatives | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-12-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100278767-A1 | Lightening Agents and/or Dyes that Contain Aldehyde(s) | CCR3, CBR3, CCRL2 | TRIM24 4273/4885TRIM33 1124/4885ALDH1A1 105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.