Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | CREBBP | Q92793 | 6/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.45 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.45 |
| ▸ | PI4KA | P42356 | 1/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.45 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | POLQ | O75417 | 1/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.43 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13260970 | 0.91 | POLQ (0.48) | L3MBTL1CREBBPDHODHHPGDNPC1 | |
| SCHEMBL3722206 | 0.75 | POLQ (0.52) | L3MBTL1CREBBPSMN1; SMN2POLQKDM4E | |
| SCHEMBL1821560 | 0.74 | KDM4E (0.71) | HPGDNPC1SMN1; SMN2POLBKDM4E | |
| SCHEMBL3724299 | 0.73 | POLQ (0.50) | L3MBTL1CREBBPSMN1; SMN2POLBTDP1 | |
| SCHEMBL4208205 | 0.73 | PIK3CG (0.51) | L3MBTL1CREBBPNPC1NAMPTPIK3CD | |
| SCHEMBL3906989 | 0.73 | PTPN1 (0.47) | L3MBTL1CREBBPNAMPTPOLQ | |
| SCHEMBL3724788 | 0.72 | L3MBTL1 (0.52) | L3MBTL1CREBBPDHODHNAMPTIKBKE | |
| SCHEMBL10094644 | 0.71 | CREBBP (0.69) | L3MBTL1CREBBPPIK3CD | |
| SCHEMBL3731303 | 0.70 | PTGS1 (0.39) | SMN1; SMN2POLBHSD17B10 | |
| SCHEMBL4638600 | 0.70 | CREBBP (0.54) | L3MBTL1CREBBPDHODHNAMPTIKBKE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093885-A1 | INHIBITORS OF AKT ACTIVITY | GLAXOSMITHKLINE LLC (US) | 2010-08-19 | — | — | WO | disclosed |