Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 4/20 | 0.43 |
| ▸ | TACR1 | P25103 | 3/20 | 0.40 |
| ▸ | F2R | P25116 | 2/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3724390 | 0.87 | F2R (0.42) | TACR1F2R | |
| SCHEMBL21381940 | 0.87 | RORC (0.48) | RORCTACR1NR1H2KDM4EPDE4B | |
| SCHEMBL1580870 | 0.86 | RORC (0.50) | RORCTACR1F2RKDM4EGPR119 | |
| SCHEMBL1053602 | 0.85 | RORC (0.44) | RORCTACR1F2RNR1H2KDM4E | |
| SCHEMBL1580729 | 0.84 | LIPE (0.48) | RORCTACR1F2RKDM4EPDE4B | |
| SCHEMBL3796145 | 0.80 | F2R (0.48) | F2R | |
| SCHEMBL3725314 | 0.80 | F2R (0.47) | RORCTACR1F2R | |
| SCHEMBL21381707 | 0.77 | MGLL (0.47) | RORCTACR1NR1H2KDM4EPDE4B | |
| SCHEMBL690145 | 0.75 | NR1H2 (0.50) | RORCNR1H2PDE4BGPR119NAMPT | |
| SCHEMBL12018646 | 0.75 | CNR1 (0.39) | RORCTACR1F2RNR1H2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010136144-A1 | SUBSTITUTED PIPERIDINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-12-02 | — | — | WO | disclosed |