Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | CASP1 | P29466 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3875281 | 0.85 | POLB (0.49) | ALDH1A1MAPTGAAKDM4ECASP1 | |
| SCHEMBL1979095 | 0.83 | ALDH1A1 (0.43) | ALDH1A1MAPTGAAKDM4ECASP1 | |
| SCHEMBL129715 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MAPTGAAKDM4ECASP1 | |
| SCHEMBL9503183 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MAPTGAAKDM4ECASP1 | |
| Hydrochloric Acid SCHEMBL29836005 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MAPTGAAKDM4ECASP1 | |
| Hydrochloric Acid SCHEMBL10397659 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MAPTGAAKDM4ECASP1 | |
| Hydrochloric Acid SCHEMBL1426463 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MAPTGAAKDM4ECASP1 | |
| Hydrochloric Acid SCHEMBL33975 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MAPTGAAKDM4ECASP1 | |
| Hydrochloric Acid SCHEMBL3248993 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MAPTGAAKDM4ECASP1 | |
| SCHEMBL3962000 | 0.79 | ALDH1A1 (0.43) | ALDH1A1MAPTGAAKDM4ECASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3096735-A1 | GRADUAL HAIRCOLOR COMPOSITIONS AND METHODS OF USING THE SAME | Combe International Ltd. (US) | 2016-11-30 | — | — | EP | claimed |
| EP-1674075-B1 | Hair colouring process comprising a cleaning step | ORÉAL L (FR) | 2016-07-20 | — | — | EP | claimed |
| WO-2015112789-A1 | GRADUAL HAIRCOLOR COMPOSITIONS AND METHODS OF USING THE SAME | COMBE INTERNATIONAL LTD. (US) | 2015-07-30 | — | — | WO | claimed |
| US-20100275388-A1 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES COMPRISING A CATIONIC CELLULOSE ETHER, A WEAKLY OXYETHYLENATED SORBITAN FATTY ACID ESTER AND OXIDATION DYES | L'OREAL S.A. (FR) | 2010-11-04 | — | — | US | claimed |
| EP-1674075-A1 | Colored hair treating process with a composition comprising a specific non ionic surfactant and use to protect the coloration | L'OREAL (FR) | 2006-06-28 | — | — | EP | claimed |
| EP-1674074-A1 | Colored hair treating process with a composition comprising a specific non ionic and/or an amphoteric and/or a mild anionic surfactant and use to protect the coloration | L'OREAL (FR) | 2006-06-28 | — | — | EP | claimed |
| US-7066968-B2 | Efficient two-step method of coloring and lightening hair with less damage | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. (US) | 2006-06-27 | — | — | US | claimed |
| US-7041142-B2 | Two step hair coloring compositions delivering deeper, long-lasting color | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. (US) | 2006-05-09 | — | — | US | claimed |
| US-20060075580-A1 | TWO STEP HAIR COLORING COMPOSITIONS DELIVERING DEEPER, LONG-LASTING COLOR | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2006-04-13 | — | — | US | claimed |
| US-20050193501-A1 | Efficient two-step method of coloring and lightening hair with less damage | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2005-09-08 | — | — | US | claimed |
| EP-0465339-A1 | Keratinous fibres dyeing process with derivatives of 4-hydroxyindol at acidic pH and compositions | L'OREAL (FR) | 1992-01-08 | — | — | EP | claimed |
| EP-0465340-A1 | Keratinous fibres dyeing process with 4-hydroxyindol at acidic pH and compositions | L'OREAL (FR) | 1992-01-08 | — | — | EP | claimed |
| EP-0459901-A1 | Process for dyeing of keratinic fibres using 2,6-dimethyl-1,4-diaminobenzene and/or 2,6-diethyl-1,4-diaminobenzene in acid medium and compositions using this process | L'OREAL (FR) | 1991-12-04 | — | — | EP | claimed |
| EP-0459900-A1 | Process for dyeing of keratinic fibres with 2,4-diamino-1,3-dimethoxybenzene in an acid medium and composition using this process | L'OREAL (FR) | 1991-12-04 | — | — | EP | claimed |
| EP-0446132-A1 | Keratinous fibres dyeing process with 6 or 7-monohydroxyindols at acidic pH and compositions | L'OREAL (FR) | 1991-09-11 | — | — | EP | claimed |
| EP-0424261-A1 | Dyeing composition containing oxidation dyes precursors and aminoindole derivatives as coupling agent | L'OREAL (FR) | 1991-04-24 | — | — | EP | claimed |
| US-4985042-A | New substituted metaaminophenols, a process for their preparation, hair-dyeing compositions containing them and a hair-dyeing process | L'OREAL (FR) | 1991-01-15 | — | — | US | claimed |
| US-4954131-A | Substituted metaaminophenols, a process for their preparation, hair-dyeing compositions containing them and a hair-dyeing process | L'OREAL (FR) | 1990-09-04 | — | — | US | claimed |
| US-4863480-A | OXIDATION COLOR DYES | THE FRENCH JOINT STOCK COMPANY "L'OREAL" (FR) | 1989-09-05 | — | — | US | claimed |
| US-4692166-A | OXIDATION COLOR DYES USED WITH DIAMINOBENZENES OR AMINO PHENOLS; MINIMIZATION OF RED HUE | L'OREAL (FR) | 1987-09-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100275388-A1 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES COMPRISING A CATIONIC CELLULOSE ETHER, A WEAKLY OXYETHYLENATED SORBITAN FATTY ACID ESTER AND OXIDATION DYES | KRT18, KRTCAP2, FASN | ALDH1A1 1792/4885MAPT 687/4885GAA 2045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.