Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3875281 | 0.83 | POLB (0.49) | ALDH1A1MAPTGAAKDM4EHTT | |
| SCHEMBL11028180 | 0.82 | ALDH1A1 (0.62) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL3732045 | 0.82 | ALDH1A1 (0.47) | ALDH1A1MAPTGAAKDM4EHTT | |
| SCHEMBL129715 | 0.80 | ALDH1A1 (0.46) | ALDH1A1MAPTGAAKDM4EHTT | |
| Hydrochloric Acid SCHEMBL33975 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MAPTGAAKDM4EHTT | |
| Hydrochloric Acid SCHEMBL29836005 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MAPTGAAKDM4EHTT | |
| Hydrochloric Acid SCHEMBL3248993 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MAPTGAAKDM4EHTT | |
| Hydrochloric Acid SCHEMBL1426463 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MAPTGAAKDM4EHTT | |
| Hydrochloric Acid SCHEMBL10397659 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MAPTGAAKDM4EHTT | |
| SCHEMBL31194867 | 0.78 | POLB (0.40) | ALDH1A1MAPTGAAKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328968-B1 | PROCESS FOR THE PREPARATION OF 4-ACYLAMINO-2-AMINO ALKOXY BENZENES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-05-12 | — | — | EP | disclosed |
| US-5047586-A | Process for the preparation of 4-acylamino-2-aminoalkoxybenzenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-10 | — | — | US | disclosed |
| EP-0328968-A2 | Process for the preparation of 4-acylamino-2-amino alkoxy benzenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-23 | — | — | EP | disclosed |
| EP-0007738-B1 | PROCESS FOR PRODUCING 2-AMINO-4-ACYLAMINOPHENYL ETHER AND 2,4-DIAMINOPHENYL ETHER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-12-29 | — | — | EP | disclosed |
| EP-0007738-A1 | Process for producing 2-amino-4-acylaminophenyl ether and 2,4-diaminophenyl ether | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-02-06 | — | — | EP | disclosed |