Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | CASP1 | P29466 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3732045 | 0.85 | ALDH1A1 (0.47) | POLBALDH1A1MAPTGAAKDM4E | |
| SCHEMBL7325807 | 0.84 | ALDH1A1 (0.50) | POLBALDH1A1MAPTGAAKDM4E | |
| SCHEMBL129715 | 0.83 | ALDH1A1 (0.46) | POLBALDH1A1MAPTGAAKDM4E | |
| SCHEMBL9503183 | 0.83 | ALDH1A1 (0.46) | POLBALDH1A1MAPTGAAKDM4E | |
| Hydrochloric Acid SCHEMBL10607534 | 0.83 | ALDH1A1 (0.53) | POLBALDH1A1MAPTGAAKDM4E | |
| SCHEMBL7519140 | 0.83 | ALDH1A1 (0.44) | POLBALDH1A1MAPTGAAKDM4E | |
| Hydrochloric Acid SCHEMBL10397659 | 0.82 | ALDH1A1 (0.49) | POLBALDH1A1MAPTGAAKDM4E | |
| Hydrochloric Acid SCHEMBL1426463 | 0.82 | ALDH1A1 (0.49) | POLBALDH1A1MAPTGAAKDM4E | |
| Hydrochloric Acid SCHEMBL29836005 | 0.82 | ALDH1A1 (0.49) | POLBALDH1A1MAPTGAAKDM4E | |
| Hydrochloric Acid SCHEMBL33975 | 0.82 | ALDH1A1 (0.49) | POLBALDH1A1MAPTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2950774-B1 | DYE COMPOSITION USING AT LEAST ONE COUPLER OF META-PHENYLENEDIAMINE TYPE SUBSTITUTED IN POSITION 4 IN A MEDIUM COMPRISING A FATTY SUBSTANCE, PROCESSES AND DEVICE | OREAL (FR) | 2018-07-25 | — | — | EP | claimed |
| EP-1674075-B1 | Hair colouring process comprising a cleaning step | ORÉAL L (FR) | 2016-07-20 | — | — | EP | claimed |
| US-20150366771-A1 | DYE COMPOSITION USING AT LEAST ONE COUPLER OF META-PHENYLENEDIAMINE TYPE SUBSTITUTED IN POSITION 4 IN A MEDIUM COMPRISING A FATTY SUBSTANCE, PROCESSES AND DEVICE | L'OREAL (FR) | 2015-12-24 | — | — | US | claimed |
| US-7485155-B2 | Process for washing colored keratinous fibers with a composition comprising at least one nonionic surfactant and method for protecting the color | L'OREAL S.A. (FR) | 2009-02-03 | — | — | US | claimed |
| US-20060156478-A1 | Process for washing colored keratinous fibers with a composition comprising at least one nonionic surfactant and method for protecting the color | L'OREAL S.A. (FR) | 2006-07-20 | — | — | US | claimed |
| US-10383803-B2 | Dye composition using at least one coupler of meta-phenylenediamine type substituted in position 4 in a medium comprising a fatty substance, processes and device | L'OREAL (FR) | 2019-08-20 | — | — | US | disclosed |
| US-10383803-B2 | Dye composition using at least one coupler of meta-phenylenediamine type substituted in position 4 in a medium comprising a fatty substance, processes and device | L'OREAL (FR) | 2019-08-20 | — | — | US | disclosed |
| EP-2950774-B1 | DYE COMPOSITION USING AT LEAST ONE COUPLER OF META-PHENYLENEDIAMINE TYPE SUBSTITUTED IN POSITION 4 IN A MEDIUM COMPRISING A FATTY SUBSTANCE, PROCESSES AND DEVICE | OREAL (FR) | 2018-07-25 | — | — | EP | disclosed |
| EP-2950774-B1 | DYE COMPOSITION USING AT LEAST ONE COUPLER OF META-PHENYLENEDIAMINE TYPE SUBSTITUTED IN POSITION 4 IN A MEDIUM COMPRISING A FATTY SUBSTANCE, PROCESSES AND DEVICE | OREAL (FR) | 2018-07-25 | — | — | EP | disclosed |
| US-20160310383-A1 | METHOD FOR DYEING KERATINOUS SUBSTANCES STARTING FROM COLOURED OLIGOMERS AND/OR POLYMERS RESULTING FROM META-PHENYLENEDIAMINES, COMPOSITION AND DYEING AGENT | L'OREAL (FR) | 2016-10-27 | — | — | US | disclosed |
| US-20160310383-A1 | METHOD FOR DYEING KERATINOUS SUBSTANCES STARTING FROM COLOURED OLIGOMERS AND/OR POLYMERS RESULTING FROM META-PHENYLENEDIAMINES, COMPOSITION AND DYEING AGENT | L'OREAL (FR) | 2016-10-27 | — | — | US | disclosed |
| US-20150366771-A1 | DYE COMPOSITION USING AT LEAST ONE COUPLER OF META-PHENYLENEDIAMINE TYPE SUBSTITUTED IN POSITION 4 IN A MEDIUM COMPRISING A FATTY SUBSTANCE, PROCESSES AND DEVICE | L'OREAL (FR) | 2015-12-24 | — | — | US | disclosed |
| US-20060156478-A1 | Process for washing colored keratinous fibers with a composition comprising at least one nonionic surfactant and method for protecting the color | L'OREAL S.A. (FR) | 2006-07-20 | — | — | US | disclosed |
| EP-0328968-B1 | PROCESS FOR THE PREPARATION OF 4-ACYLAMINO-2-AMINO ALKOXY BENZENES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-05-12 | — | — | EP | disclosed |
| US-5047586-A | Process for the preparation of 4-acylamino-2-aminoalkoxybenzenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-10 | — | — | US | disclosed |
| US-4225492-A | Water-soluble disazo dyestuffs, prepared from unsymmetrical heterocyclic diamines | CASSELLA AKTIENGESELLSCHAFT (DE) | 1980-09-30 | — | — | US | disclosed |
| US-4144231-A | Soluble trisazo dyestuffs containing a 2-phenyl-benzimidazolyl, -benzoxazolyl or -benzthiazolyl middle component | CASSELLA AKTIENGESELLSCHAFT (DE) | 1979-03-13 | — | — | US | disclosed |
| US-4144230-A | Soluble trisazo dyestuffs containing a 2-phenyl-benzimidazolyl, -benzoxazolyl or -benzthiazolyl middle component | CASSELLA AKTIENGESELLSCHAFT (DE) | 1979-03-13 | — | — | US | disclosed |
| US-4143033-A | WATER-SOLUBLE DISAZO DYESTUFFS CONTAINING A 2-PHENYL-BENZIMIDAZOLYL,-BENZOXAZOLYL OR-BENZTHIAZOLYL MIDDLE COMPONENT | CASSELLA AKTIENGESELLSCHAFT (DE) | 1979-03-06 | — | — | US | disclosed |
| US-4137228-A | HIGH TINCTORIAL STRENGTH, COLORFASTNESS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1979-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160310383-A1 | METHOD FOR DYEING KERATINOUS SUBSTANCES STARTING FROM COLOURED OLIGOMERS AND/OR POLYMERS RESULTING FROM META-PHENYLENEDIAMINES, COMPOSITION AND DYEING AGENT | KRT18, VIM, SORD | POLB 522/4885ALDH1A1 1145/4885MAPT 29/4885 |
| US-10383803-B2 | Dye composition using at least one coupler of meta-phenylenediamine type substituted in position 4 in a medium comprising a fatty substance, processes and device | FABP4, KRT18, DSG1 | POLB 579/4885ALDH1A1 317/4885MAPT 1508/4885 |
| US-20060156478-A1 | Process for washing colored keratinous fibers with a composition comprising at least one nonionic surfactant and method for protecting the color | KRT18, DSG1, DSP | POLB 538/4885ALDH1A1 2250/4885MAPT 998/4885 |
| US-20150366771-A1 | DYE COMPOSITION USING AT LEAST ONE COUPLER OF META-PHENYLENEDIAMINE TYPE SUBSTITUTED IN POSITION 4 IN A MEDIUM COMPRISING A FATTY SUBSTANCE, PROCESSES AND DEVICE | FABP4, KRT18, DSG1 | POLB 574/4885ALDH1A1 354/4885MAPT 1422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.