SCHEMBL3732050

SCHEMBL3732050

CCC(=O)ONC(=O)CCC(N)=O

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
CTSD P07339 1/20 0.32
TSHR P16473 2/20 0.32
MEN1 O00255 1/20 0.31
FAAH O00519 1/20 0.31
TP53 P04637 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C19 P33261 1/20 0.31
SOAT1 P35610 1/20 0.31
KMT2A Q03164 1/20 0.31
ALOX15 P16050 1/20 0.30
MGAM O43451 1/20 0.30
GAA P10253 1/20 0.30
SI P14410 1/20 0.30
MGAM2 Q2M2H8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27577004 0.86 ALDH1A1 (0.43) ALDH1A1CTSDTSHRMEN1FAAH
SCHEMBL28172522 0.85 TSHR (0.36) ALDH1A1TSHR
SCHEMBL23867785 0.83 ALDH1A1 (0.42) ALDH1A1CTSDTSHRMGAMGAA
SCHEMBL27407392 0.81 SOAT1 (0.46) MEN1FAAHTP53CYP1A2CYP3A4
SCHEMBL27540665 0.81 KDM4E (0.33)
SCHEMBL27645896 0.81 TSHR (0.36) ALDH1A1TSHRMEN1FAAHTP53
SCHEMBL4897752 0.80 KMT2A (0.39) ALDH1A1CTSDTSHRMEN1SOAT1
SCHEMBL321683 0.80 SOAT1 (0.49) TSHRMEN1FAAHTP53CYP1A2
SCHEMBL28053482 0.79 KDM4E (0.40) ALDH1A1TP53CYP1A2CYP3A4CYP2C19
SCHEMBL27661788 0.79 TRPA1 (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101910194-B Double affinity polypeptides for purification 科雷托公司 2017-03-08 CN disclosed
CN-105738612-A Cell detection methods and reagents having a releasable labelling moiety 美天施生物科技有限责任公司 2016-07-06 CN disclosed
CN-105683217-A Antigen binding proteins that bind to PD-1 索伦托治疗有限公司 2016-06-15 CN disclosed
CN-105524164-A Factor VIII molecules with reduced VWF binding NOVO NORDISK AS 2016-04-27 CN disclosed
CN-102770449-B Factor VIII molecules with reduced VWF binding NOVO NORDISK A/S (DK) 2016-02-24 CN disclosed
CN-105264376-A Oligosaccharide conjugates and methods of use SEC DEP FOR ENVIRONMENT FOOD AND RURAL AFFAIRS 2016-01-20 CN disclosed
CN-105050618-A Antigen binding proteins that bind to c-Met SORRENTO THERAPEUTICS INC 2015-11-11 CN disclosed
CN-105051065-A Antigen binding proteins that bind CCR2 SORRENTO THERAPEUTICS INC 2015-11-11 CN disclosed
CN-104994872-A Antigen binding proteins that bind igf1r SORRENTO THERAPEUTICS INC 2015-10-21 CN disclosed
CN-104736168-A Antigen binding proteins that bind to PD-L1 SORRENTO THERAPEUTICS INC 2015-06-24 CN disclosed
CN-100387616-C Method for obtaining antigenic structures enhancing specific cross reactivity CENTO DE INGENIERIA GENETICA Y (CU) 2008-05-14 CN disclosed
CN-100339393-C PEG-conjugates of HGF-NK 4 HOFFMANN LA ROCHE (CH) 2007-09-26 CN disclosed
CN-1997666-A Polyethylene glycol modified interferon compositions and methods of use thereof INTERMUNE INC (US) 2007-07-11 CN disclosed
CN-1938040-A Oxytocin controlled release formulations and methods of using same PR PHARMACEUTICALS (US) 2007-03-28 CN disclosed
CN-1777440-A Method for preparing site-specific protein conjugate PR PHARMACEUTICALS INC (US) 2006-05-24 CN disclosed
EP-1605894-A2 OXYTOCIN CONTROLLED RELEASE FORMULATIONS AND METHODS OF USING SAME PR Pharmaceuticals (US) 2005-12-21 EP disclosed
CN-1571679-A PEG-conjugates of HGF-NK4 HOFFMANN LA ROCHE (CH) 2005-01-26 CN disclosed
WO-2004078147-A2 OXYTOCIN CONTROLLED RELEASE FORMULATIONS AND METHODS OF USING SAME PR PHARMACEUTICALS (US) 2004-09-16 WO disclosed
CN-1446094-A Method for obtaining antigenic structures enhancing specific cross reactivity CENTO DE INGENIERIA GENETICA Y (CU) 2003-10-01 CN disclosed
CN-1230216-A Breakable signal element apparatus and method BURSTEIN LAB INC (US) 1999-09-29 CN disclosed