Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CPB1 | P15086 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TLR4 | O00206 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | PREP | P48147 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29867697 | 0.87 | KMT2A (0.45) | ALDH1A1GAACPB1CTSLCTSB | |
| SCHEMBL31287332 | 0.85 | PREP (0.49) | ALDH1A1GAACPB1CTSLCTSB | |
| SCHEMBL17591736 | 0.82 | CTSL (0.58) | ALDH1A1GAACPB1CTSLCTSB | |
| SCHEMBL4443457 | 0.81 | EPHX1 (0.53) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL28250701 | 0.81 | ALDH1A1 (0.49) | ALDH1A1GAACPB1CTSLCTSB | |
| SCHEMBL2552964 | 0.81 | EPHX1 (0.55) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL16202690 | 0.80 | ALDH1A1 (0.67) | ALDH1A1GAACPB1CTSLCTSB | |
| SCHEMBL26477499 | 0.80 | ALDH1A1 (0.67) | ALDH1A1GAACPB1CTSLCTSB | |
| SCHEMBL16400506 | 0.79 | CTSL (0.57) | ALDH1A1GAACPB1CTSLCTSB | |
| SCHEMBL17174585 | 0.78 | EPHX1 (0.61) | ALDH1A1GAACPB1CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139888-A2 | IMIDAZOÝ1,2-A¨PYRIDINE COMPOUNDS AS RECEPTOR TYROSINE KINASE INHIBITORS | Array Biopharma, Inc. (US) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008121687-A2 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS RECEPTOR TYROSINE KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2008-10-09 | — | — | WO | disclosed |