SCHEMBL3732085

SCHEMBL3732085

O=C(O)C1NC(c2ccccc2)Cc2ccccc21

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
GRIN2D O15399 1/20 0.47
GRIN3B O60391 1/20 0.47
GRIN1 Q05586 1/20 0.47
GRIN2A Q12879 1/20 0.47
GRIN2B Q13224 1/20 0.47
GRIN2C Q14957 1/20 0.47
GRIN3A Q8TCU5 1/20 0.47
PRCP P42785 1/20 0.46
OPRM1 P35372 1/20 0.41
EDNRA P25101 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
SIGMAR1 Q99720 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27398624 0.81 MAPT (0.53) TSHRNPSR1GRIN2DGRIN3BGRIN1
SCHEMBL28787105 0.81 MAPT (0.53) TSHRNPSR1GRIN2DGRIN3BGRIN1
SCHEMBL7201340 0.80 TSHR (0.51) TSHRNPSR1GRIN2DGRIN3BGRIN1
SCHEMBL1654888 0.77 CA1 (0.41) TSHRNPSR1GRIN2DGRIN3BGRIN1
SCHEMBL1325110 0.73 TSHR (0.48) TSHRNPSR1EDNRA
SCHEMBL10670425 0.73 GRIN2D (0.47) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL9608966 0.72 TSHR (0.67) TSHRNPSR1PRCPGAAMAPT
SCHEMBL21689895 0.72 TSHR (0.67) TSHRNPSR1PRCPGAAMAPT
SCHEMBL30230052 0.72 TSHR (0.67) TSHRNPSR1PRCPGAAMAPT
SCHEMBL17231978 0.72 TSHR (0.67) TSHRNPSR1PRCPGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1757604-B1 PROCESS FOR PRODUCING SOLIFENACIN OR ITS SALT ASTELLAS PHARMA INC (JP) 2012-05-30 EP disclosed
US-7829715-B2 Method for producing solifenacin or salts thereof ASTELLAS PHARMA INC. (JP) 2010-11-09 US disclosed
US-20070185329-A1 Method for producing solifenacin or salts thereof ASTELLAS PHARMA INC. 2007-08-09 US disclosed
EP-1757604-A1 PROCESS FOR PRODUCING SOLIFENACIN OR ITS SALT Astellas Pharma Inc. (JP) 2007-02-28 EP disclosed
WO-2005105795-A1 PROCESS FOR PRODUCING SOLIFENACIN OR ITS SALT ASTELLAS PHARMA INC. (JP) 2005-11-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070185329-A1 Method for producing solifenacin or salts thereof SUCNR1, GLS, CACNA1S TSHR 3759/4885NPSR1 461/4885GRIN2D 1172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.