SCHEMBL373226

SCHEMBL373226

C[Si](C)(C)O[Si](C)(C)CCC/C(C(=O)O)=C(/CCC[Si](C)(C)O[Si](C)(C)C)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FNTA P49354 3/20 0.33
FNTB P49356 3/20 0.33
THRB P10828 1/20 0.33
PGGT1B P53609 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL373228 1.00 FNTA (0.33) FNTAFNTBTHRBPGGT1B
SCHEMBL9131331 0.91 FNTA (0.31) FNTAFNTBTHRBPGGT1B
SCHEMBL8855919 0.87
SCHEMBL9126396 0.85
SCHEMBL3516149 0.85
SCHEMBL3516144 0.85
SCHEMBL373896 0.84 FNTA (0.33) FNTAFNTBTHRBPGGT1B
SCHEMBL17451083 0.84 FNTA (0.33) FNTAFNTBTHRBPGGT1B
SCHEMBL373899 0.84 FNTA (0.33) FNTAFNTBTHRBPGGT1B
SCHEMBL714095 0.84 FNTA (0.33) FNTAFNTBTHRBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025094241-A1 COMPOSITE MEMBRANE 株式会社メニコン 2025-05-08 WO disclosed
US-20180356561-A1 GEL, GEL MANUFACTURING METHOD, LENS, CONTACT LENS SURFACE MODIFIER, POLYMERIZABLE COMPOSITION, AND POLYMER JSR CORPORATION (JP) 2018-12-13 US disclosed
US-20160028090-A1 CATHODE FOR FUEL CELL TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2016-01-28 US disclosed
EP-2978057-A1 CATHODE FOR FUEL CELL Toyota Jidosha Kabushiki Kaisha (JP) 2016-01-27 EP disclosed
US-9238715-B2 Polymerizable composition for ophthalmic and medical use and antimicrobial composition obtained by polymerizing the polymerizable composition NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2016-01-19 US disclosed
US-9034942-B2 Polymer material, ophthalmic lens and contact lens MENICON CO., LTD. (JP) 2015-05-19 US disclosed
US-9017716-B2 Ophthalmic lens MENICON CO., LTD. (JP) 2015-04-28 US disclosed
US-20140163133-A1 POLYMERIZABLE COMPOSITION FOR OPHTHALMIC AND MEDICAL USE AND ANTIMICROBIAL COMPOSITION OBTAINED BY POLYMERIZING THE POLYMERIZABLE COMPOSITION MENICON CO., LTD (JP) 2014-06-12 US disclosed
EP-2180366-B1 SILICONE-CONTAINING OCULAR LENS MATERIAL WITH HIGH SAFETY AND PREPARING METHOD THEREOF MENICON CO LTD (JP) 2013-09-25 EP disclosed
US-20130202551-A1 IONIC COMPOUND, COMPOSITION, CURED MATERIAL, HYDROGEL AND OPHTHALMIC LENS MENICON CO., LTD. (JP) 2013-08-08 US disclosed
EP-2578244-A1 POLYMERIZABLE COMPOSITION FOR OPHTHALMIC AND MEDICAL USE AND ANTIBACTERIAL COMPOSITION OBTAINED BY POLYMERIZING SAME Nanyang Technological University (SG) 2013-04-10 EP disclosed
US-20120148519-A1 OPHTHALMIC LENS MENICON CO., LTD. (JP) 2012-06-14 US disclosed
EP-2453293-A1 OPHTHALMIC LENS Menicon Co., Ltd. (JP) 2012-05-16 EP disclosed
US-8124668-B2 Silicone-containing ocular lens material with high safety and preparing method thereof MENICON CO., LTD. (JP) 2012-02-28 US disclosed
EP-2410371-A1 Polymer material and ophthalmic lens Menicon Co., Ltd. (JP) 2012-01-25 EP disclosed
EP-2180366-A1 Silicone-containing ocular lens material with high safety and preparing method thereof MENICON CO., LTD. (JP) 2010-04-28 EP disclosed
US-20060142410-A1 Silicone-containing ocular lens material with high safety and preparing method thereof MENICON CO., LTD. (JP) 2006-06-29 US disclosed
EP-1582910-A1 HIGHLY SAFE SILICONE-CONTAINING MATERIAL FOR OCULAR LENS AND PROCESS FOR PRODUCING THE SAME MENICON CO., LTD. (JP) 2005-10-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120148519-A1 OPHTHALMIC LENS AQP4, CRYAA, UACA FNTA 606/4885FNTB 1350/4885THRB 2995/4885
US-20130202551-A1 IONIC COMPOUND, COMPOSITION, CURED MATERIAL, HYDROGEL AND OPHTHALMIC LENS CRYZ, CRYAA, VIL1 FNTA 1814/4885FNTB 1566/4885THRB 4713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.