Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28615277 | 0.98 | LMNA (0.47) | LMNAHCAR2THRBCHRNB2CHRNB4 | |
| Fluoride SCHEMBL28988172 | 0.81 | HCAR2 (0.44) | LMNAHCAR2THRBCYP2C19ALDH1A1 | |
| SCHEMBL5664548 | 0.81 | HCAR2 (0.43) | LMNAHCAR2THRBCHRNB2CHRNB4 | |
| Fluoride SCHEMBL28527584 | 0.80 | HCAR2 (0.42) | LMNAHCAR2THRBCHRNB2CHRNB4 | |
| Iodide SCHEMBL22042239 | 0.80 | HCAR2 (0.42) | LMNAHCAR2THRBCHRNB2CHRNB4 | |
| Hydrochloric Acid SCHEMBL5000725 | 0.80 | HCAR2 (0.42) | LMNAHCAR2THRBCHRNB2CHRNB4 | |
| SCHEMBL5580239 | 0.80 | KDM4E (0.45) | LMNAHCAR2THRBCHRNB2CHRNB4 | |
| Bromide SCHEMBL28534138 | 0.80 | HCAR2 (0.42) | LMNAHCAR2THRBCHRNB2CHRNB4 | |
| Hydrochloric Acid SCHEMBL7722976 | 0.78 | ALDH1A1 (0.44) | LMNAHCAR2THRBCHRNB2CHRNB4 | |
| SCHEMBL961211 | 0.77 | THRB (0.41) | LMNAHCAR2THRBCYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576255-B1 | Injection molding method for (meth)acrylate copolymers having tertiary ammonium groups | ROEHM GMBH & CO. KG (DE) | 2003-06-10 | — | — | US | claimed |
| US-20220287345-A1 | SOLUBILITY ENHANCEMENT OF POORLY SOLUBLE ACTIVES | EVONIK OPERATIONS GMBH (DE) | 2022-09-15 | — | — | US | disclosed |
| EP-2568967-B2 | PHARMACEUTICAL COMPOSITIONS COMPRISING HYDROMORPHONE AND NALOXONE | EURO CELTIQUE SA (LU) | 2022-07-27 | — | — | EP | disclosed |
| EP-4009961-A1 | SOLUBILITY ENHANCEMENT OF POORLY SOLUBLE ACTIVES | Evonik Operations GmbH (DE) | 2022-06-15 | — | — | EP | disclosed |
| WO-2021023857-A1 | SOLUBILITY ENHANCEMENT OF POORLY SOLUBLE ACTIVES | EVONIK OPERATIONS GMBH (DE) | 2021-02-11 | — | — | WO | disclosed |
| US-20190224130-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING HYDROMORPHONE AND NALOXONE | PURDUE PHARMA (CA) | 2019-07-25 | — | — | US | disclosed |
| EP-3505162-A1 | USE OF BINDERS FOR MANUFACTURING STORAGE STABLE FORMULATIONS | Euro-Celtique S.A. (LU) | 2019-07-03 | — | — | EP | disclosed |
| US-10113050-B2 | Powdery or granulated composition comprising a copolymer, a dicarboxylic acid and a fatty monocarboxylic acid | EVONIK ROEHM GMBH (DE) | 2018-10-30 | — | — | US | disclosed |
| EP-2568967-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING HYDROMORPHONE AND NALOXONE | EURO CELTIQUE SA (LU) | 2018-10-24 | — | — | EP | disclosed |
| EP-2603205-B1 | USE OF BINDERS FOR MANUFACTURING STORAGE STABLE FORMULATIONS | EURO CELTIQUE SA (LU) | 2018-10-03 | — | — | EP | disclosed |
| US-20050142174-A1 | Adhesive and binding agent for dermal or transdermal treatment systems | ROEHM GMBH & CO. KG | 2005-06-30 | — | — | US | disclosed |
| US-20050019381-A1 | Binding agent which is stable in storage and used for pharmaceutical applications | ROEHM GMBH & CO. KG (DE) | 2005-01-27 | — | — | US | disclosed |
| US-6846891-B2 | Coating and binding agent for oral or dermal pharmaceutical forms | ROEHM GMBH & CO. KG (DE) | 2005-01-25 | — | — | US | disclosed |
| US-20040249035-A1 | Granulate or powder for producing coating or binding agents for medicaments | PETEREIT HANS-ULRICH (DE) | 2004-12-09 | — | — | US | disclosed |
| US-20040247687-A1 | Method for production of active ingredient-containing pellets | ROEHM GMBH & CO. KG (DE) | 2004-12-09 | — | — | US | disclosed |
| US-20030220413-A1 | Coating and binding agent for oral or dermal pharmaceutical forms | ROEHM GMBH & CO. KG (DE) | 2003-11-27 | — | — | US | disclosed |
| US-6624210-B1 | (Meth)acrylate ester copolymer with (meth)acrylate containing tertiary amine group, plasticizer, and emulsifier; powders, pastes, aqueous suspension; encapsulation; drug delivery | ROEHM GMBH & CO. KG (DE) | 2003-09-23 | — | — | US | disclosed |
| US-6576255-B1 | Injection molding method for (meth)acrylate copolymers having tertiary ammonium groups | ROEHM GMBH & CO. KG (DE) | 2003-06-10 | — | — | US | disclosed |
| US-20030064036-A1 | Coating and binding agent for pharmaceutical formulations with improved storage stability | ROEHM GMBH (DE) | 2003-04-03 | — | — | US | disclosed |
| US-4705695-A | AMMONIUM SALT OF TERTIARY AMINE SUBSTITUTED ACRYLIC POLYMER | ROHM GMBH CHEMISCHE FABRIK (DE) | 1987-11-10 | — | — | US | disclosed |