Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL3733382

CCOC(=O)CCCO.OCCOCCO

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.53
TSHR P16473 3/20 0.45
CYP4F2 P78329 3/20 0.45
CYP4A11 Q02928 3/20 0.45
ALDH1A1 P00352 3/20 0.44
DGKA P23743 1/20 0.44
NR1I2 O75469 1/20 0.43
PGR P06401 1/20 0.43
ADORA3 P0DMS8 1/20 0.43
PTGS2 P35354 1/20 0.43
PDE4D Q08499 1/20 0.43
MGAM O43451 1/20 0.43
GAA P10253 1/20 0.43
SI P14410 1/20 0.43
MGAM2 Q2M2H8 1/20 0.43
EPHX2 P34913 1/20 0.43
MGLL Q99685 1/20 0.42
CYP3A4 P08684 1/20 0.41
ALOX15 P16050 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19666668 0.92 CYP1A2 (0.53) CYP1A2TSHRCYP4F2CYP4A11ALDH1A1
SCHEMBL19666688 0.90 CYP1A2 (0.52) CYP1A2TSHRCYP4F2CYP4A11ALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL15375866 0.90 TSHR (0.54) CYP1A2TSHRCYP4F2CYP4A11ALDH1A1
SCHEMBL6061000 0.90 DGKA (0.52) CYP1A2TSHRCYP4F2CYP4A11ALDH1A1
SCHEMBL6736 0.89
Di(Hydroxyethyl)Ether SCHEMBL8090815 0.89 DGKA (0.60) CYP1A2TSHRDGKAEPHX2MGLL
2-Ethoxyethanol SCHEMBL28173960 0.88 ALDH1A1 (0.56) CYP1A2TSHRCYP4F2CYP4A11ALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL29039786 0.88 GPR84 (0.48) CYP1A2TSHRCYP4F2CYP4A11ALDH1A1
SCHEMBL580820 0.88 ALDH1A1 (0.48) CYP1A2TSHRCYP4F2CYP4A11ALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL28213240 0.88 GAA (0.52) CYP1A2TSHRCYP4F2CYP4A11ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7825178-B2 Leveling agent for floor polish and aqueous floor polish composition DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2010-11-02 US disclosed
US-20070289481-A1 Leveling Agent for Floor Polish and Aqueous Floor Polish Composition DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2007-12-20 US disclosed
CN-101044221-A Leveling agent for floor polish and aqueous floor polish composition DAIHACHI CHEM IND (JP) 2007-09-26 CN disclosed