Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.61 |
| ▸ | POLB | P06746 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | GLS | O94925 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2644442 | 0.76 | ALDH1A1 (1.00) | ALDH1A1POLBHPGDLMNAHTT | |
| Hydrogen Sulfide SCHEMBL28084028 | 0.74 | ALDH1A1 (0.96) | ALDH1A1POLBHPGDLMNAHTT | |
| SCHEMBL15884611 | 0.74 | ALDH1A1 (0.70) | ALDH1A1POLBHPGDLMNAHTT | |
| SCHEMBL15472914 | 0.73 | ALDH1A1 (0.61) | ALDH1A1POLBHPGDLMNAHTT | |
| SCHEMBL3027076 | 0.73 | ALDH1A1 (1.00) | ALDH1A1POLBHPGDLMNAHTT | |
| SCHEMBL602492 | 0.73 | ALDH1A1 (0.69) | ALDH1A1POLBHPGDLMNAHTT | |
| SCHEMBL4220065 | 0.73 | ALDH1A1 (0.69) | ALDH1A1POLBHPGDLMNAHTT | |
| SCHEMBL9357255 | 0.71 | TAAR1 (0.56) | ALDH1A1TAAR1MAPT | |
| SCHEMBL601912 | 0.69 | ALDH1A1 (0.58) | ALDH1A1POLBHPGDLMNAHTT | |
| SCHEMBL3467136 | 0.69 | ALDH1A1 (0.63) | ALDH1A1POLBHPGDLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120669-A1 | THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE | BOUILLOT ANNE MARIE JEANNE | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120669-A1 | THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE | SCD, SCD5, FADS2 | ALDH1A1 458/4885POLB 3408/4885HPGD 203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.