Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | QPCT | Q16769 | 2/20 | 0.43 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.43 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19793294 | 0.85 | ATM (0.63) | ALDH1A1LMNAHPGDPOLBHTT | |
| SCHEMBL11749002 | 0.83 | ALDH1A1 (0.53) | ALDH1A1LMNAHPGDPOLBHTT | |
| SCHEMBL3467590 | 0.81 | LMNA (0.61) | ALDH1A1LMNAHPGDPOLBHTT | |
| SCHEMBL31409666 | 0.81 | IDO1 (0.42) | ALDH1A1LMNAHPGDPOLBHTT | |
| SCHEMBL602492 | 0.81 | ALDH1A1 (0.69) | ALDH1A1LMNAHPGDPOLBHTT | |
| SCHEMBL10284718 | 0.80 | HSD11B1 (0.44) | ALDH1A1LMNAHPGDLTA4HIDO1 | |
| SCHEMBL15884611 | 0.79 | ALDH1A1 (0.70) | ALDH1A1LMNAHPGDPOLBHTT | |
| SCHEMBL11750879 | 0.78 | ALDH1A1 (0.56) | ALDH1A1LMNAHPGDPOLBHTT | |
| SCHEMBL4220065 | 0.77 | ALDH1A1 (0.69) | ALDH1A1LMNAHPGDPOLBHTT | |
| SCHEMBL3027076 | 0.77 | ALDH1A1 (1.00) | ALDH1A1LMNAHPGDPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025026997-A1 | SUBSTITUED BICYCLIC HETEROCYCLIC YAP-TEAD AND/OR TAZ-TEAD INHIBITORS | MERCK PATENT GMBH (DE) | 2025-02-06 | — | — | WO | disclosed |
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |
| US-20100120669-A1 | THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE | BOUILLOT ANNE MARIE JEANNE | 2010-05-13 | — | — | US | disclosed |
| US-4054665-A | 2-Amino-5-(trifluoromethylphenylalkyl)-1,3,4 thiadiazoles used in the treatment of insomnia and anxiety | SANDOZ, INC. (US) | 1977-10-18 | — | — | US | disclosed |
| US-3965110-A | 2-Amino-5-(trifluoromethyl phenylalkyl)-1,3,4-thiadiazoles | SANDOZ, INC. (US) | 1976-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120669-A1 | THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE | SCD, SCD5, FADS2 | ALDH1A1 458/4885LMNA 2761/4885HPGD 203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.