Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2120830 | 0.90 | TSHR (0.65) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL3733736 | 0.86 | TSHR (0.44) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL15636 | 0.84 | THRB (0.74) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL6142874 | 0.84 | THRB (0.74) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL8773894 | 0.83 | THRB (0.57) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL27278 | 0.83 | TSHR (0.45) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL13562453 | 0.82 | THRB (0.52) | THRBTSHRALDH1A1POLBAPEX1 | |
| Ethylene Glycol SCHEMBL57404 | 0.82 | THRB (0.65) | THRBTSHRALDH1A1POLBAPEX1 | |
| Ethylene Glycol SCHEMBL8740543 | 0.82 | THRB (0.65) | THRBTSHRALDH1A1POLBAPEX1 | |
| Ethylene SCHEMBL2367613 | 0.82 | THRB (0.71) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0158478-B1 | METHACRYLIC RESIN MOLDING MATERIAL AND METHOD FOR PRODUCTION THEREOF | Kuraray Co., Ltd. (JP) | 1992-07-22 | — | — | EP | disclosed |
| US-4791184-A | PARTIALLY CROSSLINKED GEL BY STOICHIOMETRIC CONTROL OF THE INITIATED POLYMERIZATION OF METHACRYLATE AND CROSSLINKING AGENT; HEAT AND SOLVENT RESISTANCE | KYOWA GAS CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-12-13 | — | — | US | disclosed |
| EP-0158478-A2 | Methacrylic resin molding material and method for production thereof | Kuraray Co., Ltd. (JP) | 1985-10-16 | — | — | EP | disclosed |