Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28153022 | 0.77 | AKT1 (0.41) | ALDH1A1TDP1MAPK1MAPTCES1 | |
| SCHEMBL4787335 | 0.77 | AKT1 (0.41) | ALDH1A1TDP1MAPK1MAPTCES1 | |
| SCHEMBL229640 | 0.74 | LMNA (0.58) | ALDH1A1TDP1MAPK1MAPTCES1 | |
| Benzene SCHEMBL28103328 | 0.74 | LMNA (0.58) | ALDH1A1TDP1MAPK1MAPTCES1 | |
| SCHEMBL2841791 | 0.73 | LMNA (0.56) | ALDH1A1TDP1MAPK1MAPTCES1 | |
| SCHEMBL4528180 | 0.73 | LMNA (0.56) | ALDH1A1TDP1MAPK1MAPTCES1 | |
| Ammonia Solution, Strong SCHEMBL4978199 | 0.73 | LMNA (0.56) | ALDH1A1TDP1MAPK1MAPTCES1 | |
| SCHEMBL27989259 | 0.73 | LMNA (0.56) | ALDH1A1TDP1MAPK1MAPTCES1 | |
| SCHEMBL21325951 | 0.73 | LMNA (0.56) | ALDH1A1TDP1MAPK1MAPTCES1 | |
| SCHEMBL8422588 | 0.73 | LMNA (0.56) | ALDH1A1TDP1MAPK1MAPTCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1350816-B1 | ACTIVE ENERGY RAY CURABLE COMPOSITION FOR COATING OPTICAL DISK AND OPTICAL DISK | MITSUBISHI RAYON CO (JP) | 2010-06-02 | — | — | EP | disclosed |
| US-7344768-B2 | Active energy ray curable composition for coating optical disk and optical disk | MITSUBISHI RAYON CO., LTD. (JP) | 2008-03-18 | — | — | US | disclosed |
| US-7341771-B2 | Active energy ray curable composition for coating optical disk and optical disk | MITSUBISHI RAYON CO., LTD. (JP) | 2008-03-11 | — | — | US | disclosed |
| US-7132460-B2 | Active energy ray curable composition for coating optical disk and optical disk | MITSUBISHI RAYON CO., LTD. (JP) | 2006-11-07 | — | — | US | disclosed |
| US-20060167200-A1 | Active energy ray curable composition for coating optical disk and optical disk | MITSUBISHI RAYON CO., LIMITED (JP) | 2006-07-27 | — | — | US | disclosed |
| US-20060166140-A1 | Active energy ray curable composition for coating optical disk and optical disk | MITSUBISHI RAYON CO., LIMITED (JP) | 2006-07-27 | — | — | US | disclosed |
| US-20040013976-A1 | Active energy ray curable composition for coating optical disk and optical disk | MITSUBISHI CHEMICAL CORPORATION (JP) | 2004-01-22 | — | — | US | disclosed |
| EP-1350816-A1 | ACTIVE ENERGY RAY CURABLE COMPOSITION FOR COATING OPTICAL DISK AND OPTICAL DISK | Mitsubishi Rayon Co., Ltd. (JP) | 2003-10-08 | — | — | EP | disclosed |
| EP-0750631-B1 | NOVEL MERCAPTOACETYLAMIDO 1,3,4,5-TETRAHYDRO-BENZO(C)AZEPIN-3-ONE DISULFIDE DERIVATIVES USEFUL AS INHIBITORS OF ENKEPHALINASE AND ACE | MERRELL PHARMA INC (US) | 2000-04-05 | — | — | EP | disclosed |
| US-5880119-A | Mercaptoacetylamino 1,3,4,5-tetrahydro-benzo(C)azepin-2-one disulfide derivatives useful as inhibitors of enkephalinase and ACE | MERRELL PHARMACEUTICALS INC. (US) | 1999-03-09 | — | — | US | disclosed |
| US-5731306-A | Mercaptoacetylamido 1,3,4,5-tetrahydro-benzo c!azepin-3-one disulfide derivatives useful as inhibitors of enkephalinase and ace | AVENTISUB II INC. | 1998-03-24 | — | — | US | disclosed |
| EP-0750631-A1 | NOVEL MERCAPTOACETYLAMIDO 1,3,4,5-TETRAHYDRO-BENZO(C)AZEPIN-3-ONE DISULFIDE DERIVATIVES USEFUL AS INHIBITORS OF ENKEPHALINASE AND ACE | MERRELL PHARMACEUTICALS INC. (US) | 1997-01-02 | — | — | EP | disclosed |
| WO-1995021854-A1 | NOVEL MERCAPTOACETYLAMIDO 1,3,4,5-TETRAHYDRO-BENZO[C]AZEPIN-3-ONE DISULFIDE DERIVATIVES USEFUL AS INHIBITORS OF ENKEPHALINASE AND ACE | MERRELL PHARMACEUTICALS INC. (US) | 1995-08-17 | — | — | WO | disclosed |
| EP-0640086-A1 | NOVEL MERCAPTOACETYLAMIDO PYRIDAZO 1,2]PYRIDAZINE, PYRAZOLO 1,2]PYRIDAZINE, PYRIDAZO 1,2-a] 1,2]DIAZEPINE AND PYRAZOLO 1,2-a] 1,2]DIAZEPINE DERIVATIVES USEFUL AS INHIBITORS OF ENKEPHALINASE AND ACE | MERRELL PHARMACEUTICALS INC. (US) | 1995-03-01 | — | — | EP | disclosed |
| WO-1993023403-A1 | NOVEL MERCAPTOACETYLAMIDO PYRIDAZO[1,2]PYRIDAZINE, PYRAZOLO[1,2]PYRIDAZINE, PYRIDAZO[1,2-a][1,2]DIAZEPINE AND PYRAZOLO[1,2-a][1,2]DIAZEPINE DERIVATIVES USEFUL AS INHIBITORS OF ENKEPHALINASE AND ACE | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-11-25 | — | — | WO | disclosed |