SCHEMBL4787335

SCHEMBL4787335

C=COC(=S)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.41
ALDH1A1 P00352 4/20 0.37
MAPT P10636 3/20 0.37
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
HPGD P15428 2/20 0.35
HSP90AA1 P07900 1/20 0.35
GAA P10253 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
LMNA P02545 2/20 0.35
POLB P06746 1/20 0.35
CES1 P23141 2/20 0.34
MAPK1 P28482 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
KDM4E B2RXH2 1/20 0.34
CYP3A4 P08684 1/20 0.34
ALOX15 P16050 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
F2 P00734 1/20 0.34
TSHR P16473 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28153022 1.00 AKT1 (0.41) AKT1ALDH1A1MAPTMEN1KMT2A
SCHEMBL7767010 0.78 ALDH1A1 (0.39) ALDH1A1MAPTMEN1KMT2AHPGD
SCHEMBL3733763 0.77 ALDH1A1 (0.43) AKT1ALDH1A1MAPTMEN1KMT2A
SCHEMBL8423603 0.77 CYP3A4 (0.48) AKT1ALDH1A1MAPTMEN1KMT2A
Thiobenzoic Acid SCHEMBL10911571 0.77 CYP3A4 (0.44) AKT1ALDH1A1MAPTMEN1KMT2A
SCHEMBL7771235 0.77 KDM4E (0.51) ALDH1A1MAPTMEN1KMT2AHPGD
Benzoic Acid Vinyl Ester SCHEMBL14903 0.73 LMNA (0.56) AKT1ALDH1A1MAPTKMT2ALMNA
Benzoic Acid Vinyl Ester SCHEMBL28106984 0.73 LMNA (0.56) AKT1ALDH1A1MAPTKMT2ALMNA
SCHEMBL896085 0.73 AKT1 (0.41) AKT1ALDH1A1L3MBTL1LMNAPOLB
SCHEMBL27979953 0.72 MAPT (0.42) ALDH1A1MAPTLMNAPOLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8193270-B2 Method of making composites and nanocomposites 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-06-05 US disclosed
WO-2008103593-A1 POWDER COATING FLUOROPOLYMER COMPOSITIONS WITH DEPROTECTABLE AROMATIC MATERIALS 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-08-28 WO disclosed
EP-1853649-A1 METHOD OF MAKING NANOCOMPOSITES 3M Innovative Properties Company (US) 2007-11-14 EP disclosed
WO-2006065357-A1 METHOD OF MAKING NANOCOMPOSITES 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-06-22 WO disclosed
US-20060128867-A1 Method of making composites and nanocomposites 3M INNOVATIVE PROPERTIES COMPANY 2006-06-15 US disclosed
EP-0711813-B1 Antifouling coating composition HITACHI CHEMICAL CO LTD (JP) 2001-07-25 EP disclosed
EP-0757060-B1 Process for producing vinyl alcohol polymer KURARAY CO (JP) 1999-10-20 EP disclosed
US-5773508-A BIODEGRADABLE POLYMER OF ADDITION COPOLYMERS FOR PROTECTIVE COATINGS HITACHI CHEMICAL COMPANY, LTD. (JP) 1998-06-30 US disclosed
US-5710211-A REACTION OF POLYMER WITH COMPOUND HAVING A THIOL OR THIOESTER AND HYDROLYSIS TO FORM VINYL ALCOHOL KURARAY CO., LTD. (JP) 1998-01-20 US disclosed
EP-0757060-A2 Process for producing vinyl alcohol polymer KURARAY CO., LTD. (JP) 1997-02-05 EP disclosed
EP-0711813-A2 Coating varnish composition and antifouling coating composition Hitachi Chemical Co., Ltd. (JP) 1996-05-15 EP disclosed