Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | CHAT | P28329 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL373566 | 1.00 | TRPA1 (0.36) | TRPA1MAOBIDO1KMT2AMEN1 | |
| SCHEMBL373534 | 1.00 | TRPA1 (0.36) | TRPA1MAOBIDO1KMT2AMEN1 | |
| SCHEMBL372834 | 1.00 | TRPA1 (0.36) | TRPA1MAOBIDO1KMT2AMEN1 | |
| SCHEMBL373819 | 1.00 | TRPA1 (0.36) | TRPA1MAOBIDO1KMT2AMEN1 | |
| SCHEMBL373307 | 0.98 | TRPA1 (0.37) | TRPA1MAOBIDO1KMT2AMEN1 | |
| SCHEMBL373740 | 0.89 | MAOB (0.41) | TRPA1MAOBIDO1KMT2AMEN1 | |
| SCHEMBL18380875 | 0.89 | MAOB (0.41) | TRPA1MAOBIDO1KMT2AMEN1 | |
| SCHEMBL25210074 | 0.85 | MAOB (0.44) | TRPA1MAOBKMT2AMEN1PKM | |
| SCHEMBL12393026 | 0.85 | MAOB (0.44) | TRPA1MAOBKMT2AMEN1PKM | |
| SCHEMBL2037295 | 0.84 | TRPA1 (0.37) | TRPA1MAOBIDO1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0770888-B1 | Low water-absorptive ocular lens material, low water-absorptive ocular lens shaped product made thereof, low water-absorptive ocular lens made thereof and process for its production | MENICON CO LTD (JP) | 2004-08-04 | — | — | EP | claimed |
| US-5670594-A | POLYDIMETHYLSILOXANE POLYMERS WITH VINYL OR ACRYLATE GROUPS FOR INTRAOCULAR LENSES | MENICON CO., LTD. (JP) | 1997-09-23 | — | — | US | claimed |
| EP-0600269-A2 | Soft ocular lens material | Menicon Co., Ltd. (JP) | 1994-06-08 | — | — | EP | claimed |
| US-12428390-B2 | Chromene compound and photochromic optical article | TOKUYAMA CORPORATION (JP) | 2025-09-30 | — | — | US | disclosed |
| EP-3822296-B1 | POLYMER MATERIAL | MENICON CO LTD (JP) | 2025-09-10 | — | — | EP | disclosed |
| WO-2025094241-A1 | COMPOSITE MEMBRANE | 株式会社メニコン | 2025-05-08 | — | — | WO | disclosed |
| US-20250115701-A1 | POLYMER MATERIAL | MENICON CO., LTD. (JP) | 2025-04-10 | — | — | US | disclosed |
| US-12239527-B2 | Method of absorbing or discharging water of ophthalmic medical device and ophthalmic medical device | TOHOKU UNIVERSITY (JP) | 2025-03-04 | — | — | US | disclosed |
| US-12209154-B2 | Polymer material | MENICON CO., LTD. (JP) | 2025-01-28 | — | — | US | disclosed |
| EP-3995493-B1 | CHROMENE COMPOUND AND PHOTOCHROMIC OPTICAL ARTICLE | TOKUYAMA CORP (JP) | 2024-07-03 | — | — | EP | disclosed |
| US-20240026145-A1 | OPHTHALMIC LENS | MENICON CO., LTD. (JP) | 2024-01-25 | — | — | US | disclosed |
| EP-0381005-B1 | Ocular lens material | MENICON CO LTD (JP) | 1995-01-11 | — | — | EP | disclosed |
| US-5346946-A | Polysiloxane macromonomer | MENICON CO., LTD (JP) | 1994-09-13 | — | — | US | disclosed |
| EP-0600269-A2 | Soft ocular lens material | Menicon Co., Ltd. (JP) | 1994-06-08 | — | — | EP | disclosed |
| EP-0584826-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 1994-03-02 | — | — | EP | disclosed |
| EP-0584764-A1 | Ocular lens material | Menicon Co., Ltd. (JP) | 1994-03-02 | — | — | EP | disclosed |
| EP-0578087-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 1994-01-12 | — | — | EP | disclosed |
| US-5041511-A | Vinyl benzene acrylate or methacrylate crosslinking agent | MENICON CO., LTD. (JP) | 1991-08-20 | — | — | US | disclosed |
| EP-0381005-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 1990-08-08 | — | — | EP | disclosed |
| US-4594401-A | Oxygen permeable hard contact lens formed from styrene monomer containing a silyl or siloxane group | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1986-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12428390-B2 | Chromene compound and photochromic optical article | CRY1, CRY2, RAD51 | TRPA1 228/4885MAOB 3201/4885IDO1 3706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.