Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | UNG | P13051 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 2/20 | 0.42 |
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29622470 | 1.00 | FFAR1 (0.62) | FFAR1ALDH1A1CYP2A6APPCA12 | |
| SCHEMBL10633500 | 0.94 | FFAR1 (0.58) | FFAR1ALDH1A1CYP2A6APPCA12 | |
| SCHEMBL9559955 | 0.84 | FFAR1 (0.52) | FFAR1ALDH1A1CYP2A6CA12CA1 | |
| SCHEMBL9191697 | 0.83 | FFAR1 (0.51) | FFAR1ALDH1A1CYP2A6UNGMAOA | |
| SCHEMBL7054246 | 0.82 | FFAR1 (0.54) | FFAR1ALDH1A1CA12CA1CA2 | |
| SCHEMBL9699028 | 0.82 | FFAR1 (0.49) | FFAR1ALDH1A1CYP2A6CA12CA1 | |
| SCHEMBL27771764 | 0.81 | APP (0.52) | FFAR1APPCA12CA1CA2 | |
| SCHEMBL9195433 | 0.81 | TDP1 (0.52) | FFAR1ALDH1A1CYP2A6APPCA12 | |
| SCHEMBL1816905 | 0.80 | ALDH1A1 (0.59) | FFAR1ALDH1A1CYP2A6APPCA12 | |
| SCHEMBL14919859 | 0.80 | FFAR1 (0.48) | FFAR1ALDH1A1CYP2A6UNG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114437350-B | Polyimide resin and preparation method and application thereof | 波米科技有限公司 | 2022-09-16 | — | — | CN | claimed |
| CN-114437350-A | Polyimide resin and preparation method and application thereof | 波米科技有限公司 | 2022-05-06 | — | — | CN | claimed |
| CN-114315686-A | Alkynyl-containing diamine, preparation method thereof and application thereof in preparation of photosensitive resin composition | 波米科技有限公司 | 2022-04-12 | — | — | CN | claimed |
| CN-114437350-B | Polyimide resin and preparation method and application thereof | 波米科技有限公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-114315686-B | Alkynyl-containing diamine, preparation method thereof and application thereof in preparation of photosensitive resin composition | 波米科技有限公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-114751806-A | Diaryl acetylene compound and preparation method thereof | 上海泰坦科技股份有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-114437350-A | Polyimide resin and preparation method and application thereof | 波米科技有限公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-114315686-A | Alkynyl-containing diamine, preparation method thereof and application thereof in preparation of photosensitive resin composition | 波米科技有限公司 | 2022-04-12 | — | — | CN | disclosed |
| US-10934395-B2 | Polybenzimidazole oligomers with reactive end groups | PBI PERFORMANCE PRODUCTS, INC. (US) | 2021-03-02 | — | — | US | disclosed |
| US-20100279936-A1 | SUBSTITUTED ACETYLENIC COMPOUNDS USEFUL FOR THE TREATMENT OF DISEASES | LEO PHARMA A/S (DK) | 2010-11-04 | — | — | US | disclosed |
| EP-2061449-A1 | SUBSTITUTED ACETYLENIC COMPOUNDS USEFUL FOR THE TREATMENT OF DISEASES | Leo Pharma A/S (DK) | 2009-05-27 | — | — | EP | disclosed |
| EP-0540673-A4 | — | — | 1994-04-27 | — | — | EP | disclosed |
| EP-0540673-A1 | ACETYLENE DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY. | ABBOTT LAB (US) | 1993-05-12 | — | — | EP | disclosed |
| US-5202349-A | Lipoxygenase inhibitors, antiasthatics | GRUENENTHAL GMBH (DE) | 1993-04-13 | — | — | US | disclosed |
| US-5138028-A | Composites, molding materials, adhesives, electronics | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1992-08-11 | — | — | US | disclosed |
| WO-1992001682-A1 | ACETYLENE DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LABORATORIES (US) | 1992-02-06 | — | — | WO | disclosed |
| EP-0468281-A1 | Substituted phenylacetylenes, pharmaceuticals containing them and methods for the preparation of these compounds and pharmaceuticals | Grünenthal GmbH (DE) | 1992-01-29 | — | — | EP | disclosed |
| EP-0443352-A2 | Polyimides end-capped with diaryl substituted acetylene | National Starch and Chemical Investment Holding Corporation (US) | 1991-08-28 | — | — | EP | disclosed |
| EP-0279921-A2 | Phenylacetylene-substituted schiff's base momomers and electroconductive polymers | National Starch and Chemical Investment Holding Corporation (US) | 1988-08-31 | — | — | EP | disclosed |
| US-4730032-A | MOLDING MATERIALS | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1988-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100279936-A1 | SUBSTITUTED ACETYLENIC COMPOUNDS USEFUL FOR THE TREATMENT OF DISEASES | C1R, C3AR1, PTH1R | FFAR1 232/4885ALDH1A1 1976/4885CYP2A6 42/4885 |
| US-10934395-B2 | Polybenzimidazole oligomers with reactive end groups | PBRM1, PHB2, PHB1 | FFAR1 4041/4885ALDH1A1 3951/4885CYP2A6 4081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.