SCHEMBL3736016

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3093088	0.82	HSP90AA1 (0.38)	PREPCA12CA1CA9TSHR
	SCHEMBL3726821	0.81	TSHR (0.46)	CA12CA1CA9TSHR
	SCHEMBL4520328	0.79	NPC1 (0.33)	TSHRALDH1A1KDM4ELMNAMAPT
	SCHEMBL3090227	0.77	TSHR (0.52)	TSHRALDH1A1LMNA
	SCHEMBL6763899	0.75	PREP (0.53)	PREPCA12CA1CA9ALDH1A1
	SCHEMBL1344540	0.74	TSHR (0.50)	CA12CA1CA9TSHRALDH1A1
	SCHEMBL7632848	0.73	TSHR (0.44)	TSHRALDH1A1KDM4ELMNAMAPT
	SCHEMBL327430	0.70	GLA (0.51)	TSHRALDH1A1KDM4ELMNAMAPT
	SCHEMBL9778743	0.70	MAOA (0.53)	TSHRALDH1A1KDM4ELMNAMAPT
	SCHEMBL8454387	0.70	PREP (0.41)	PREPCA12CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.