Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 1/20 | 0.69 |
| ▸ | TOP2A | P11388 | 4/20 | 0.57 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.51 |
| ▸ | ACP1 | P24666 | 1/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.49 |
| ▸ | NCF1 | P14598 | 2/20 | 0.48 |
| ▸ | FLT3 | P36888 | 4/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16895289 | 0.88 | TOP1 (0.54) | TOP1TOP2APOLBGAAFLT3 | |
| Hydrochloric Acid SCHEMBL3736529 | 0.85 | TERT (0.55) | TOP1TOP2ATLR9CSNK2A1POLB | |
| SCHEMBL5780878 | 0.84 | TOP1 (0.61) | TOP1TOP2ATLR9ACP1CSNK2A1 | |
| SCHEMBL26843508 | 0.82 | TOP1 (0.78) | TOP1TOP2ATLR9ACP1CSNK2A1 | |
| SCHEMBL30479 | 0.82 | TOP1 (1.00) | TOP1TOP2ATLR9ACP1CSNK2A1 | |
| SCHEMBL29372771 | 0.82 | TOP1 (1.00) | TOP1TOP2ATLR9ACP1CSNK2A1 | |
| Hydrochloric Acid SCHEMBL29914031 | 0.81 | TOP1 (0.98) | TOP1TOP2ATLR9ACP1CSNK2A1 | |
| Hydrochloric Acid SCHEMBL1333536 | 0.81 | TOP1 (0.98) | TOP1TOP2ATLR9ACP1CSNK2A1 | |
| Hydrochloric Acid SCHEMBL7823442 | 0.81 | TOP1 (0.76) | TOP1TOP2ATLR9CSNK2A1GAA | |
| SCHEMBL3742852 | 0.81 | TERT (0.57) | TOP1TOP2APOLBRAD52FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829567-B2 | Imino-indeno[1,2-c] quinoline derivatives, their preparation processes, and pharmaceutical compositions comprising the same | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2010-11-09 | — | — | US | disclosed |
| US-20090111987-A1 | Imino-Indeno[1,2-c] quinoline derivatives, their preparation processes, and pharmaceutical compositions comprising the same | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111987-A1 | Imino-Indeno[1,2-c] quinoline derivatives, their preparation processes, and pharmaceutical compositions comprising the same | IMPA1, IMPDH1, IPO5 | TOP1 265/4885TOP2A 480/4885TLR9 2929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.