Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 3/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30591144 | 1.00 | SLC9A1 (0.49) | SLC9A1KEAP1TSHRNPSR1RXFP1 | |
| SCHEMBL29399678 | 0.98 | SLC9A1 (0.50) | SLC9A1KEAP1TSHRNPSR1RXFP1 | |
| Fluoride Ion SCHEMBL6345 | 0.97 | SLC9A1 (0.49) | SLC9A1KEAP1TSHRNPSR1RXFP1 | |
| Bromide SCHEMBL30556235 | 0.97 | SLC9A1 (0.49) | SLC9A1KEAP1TSHRNPSR1RXFP1 | |
| Phosphine SCHEMBL30298295 | 0.97 | SLC9A1 (0.49) | SLC9A1KEAP1TSHRNPSR1RXFP1 | |
| SCHEMBL1497619 | 0.92 | SLC9A1 (0.45) | SLC9A1KEAP1TSHRNPSR1RXFP1 | |
| SCHEMBL28432280 | 0.92 | SLC9A1 (0.45) | SLC9A1KEAP1TSHRNPSR1RXFP1 | |
| SCHEMBL29352246 | 0.92 | SLC9A1 (0.45) | SLC9A1KEAP1TSHRNPSR1RXFP1 | |
| SCHEMBL7270165 | 0.91 | SLC9A1 (0.44) | SLC9A1KEAP1TSHRNPSR1RXFP1 | |
| SCHEMBL936125 | 0.90 | SLC9A1 (0.42) | SLC9A1KEAP1TSHRNPSR1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10752977-B2 | Palladium separating agent, method for producing same and use of same | TOSOH CORPORATION (JP) | 2020-08-25 | — | — | US | disclosed |
| EP-2765208-B1 | PALLADIUM SEPARATING AGENT, METHOD FOR PRODUCING SAME AND USE OF SAME | TOSOH CORP (JP) | 2017-02-01 | — | — | EP | disclosed |
| EP-2231621-B1 | PROCESS FOR PREPARING N-SUBSTITUTED HYDROXYPYRIMIDINONE CARBOXAMIDES | MERCK SHARP & DOHME (US) | 2016-11-02 | — | — | EP | disclosed |
| US-20160152607-A1 | MALEIC ACID DERIVATIVE, PRODUCTION METHOD FOR SAME, AND ANTI-CANCER COMPOSITION COMPRISING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2016-06-02 | — | — | US | disclosed |
| EP-3006428-A1 | NOVEL MALEIC ACID DERIVATIVE, PRODUCTION METHOD FOR SAME AND ANTI-CANCER COMPOSITION COMPRISING SAME | Medicinal Bioconvergence Research Center (KR) | 2016-04-13 | — | — | EP | disclosed |
| US-20140248198-A1 | PALLADIUM SEPARATING AGENT, METHOD FOR PRODUCING SAME AND USE OF SAME | TOSOH CORPORATION (JP) | 2014-09-04 | — | — | US | disclosed |
| EP-2765208-A1 | PALLADIUM SEPARATING AGENT, METHOD FOR PRODUCING SAME AND USE OF SAME | Tosoh Corporation (JP) | 2014-08-13 | — | — | EP | disclosed |
| US-20100280244-A1 | PROCESS FOR PREPARING N-SUBSTITUTED HYDROXYPYRIMIDINONE CARBOXAMIDES | MERCK SHARP & DOHME LLC | 2010-11-04 | — | — | US | disclosed |
| EP-1274696-A1 | OXIME DERIVATIVES FOR CONTROLLING UNDESIRED MICROORGANISMS AND ANIMAL PESTS | Bayer CropScience AG (DE) | 2003-01-15 | — | — | EP | disclosed |
| WO-2001072726-A1 | OXIME DERIVATIVES FOR CONTROLLING UNDESIRED MICROORGANISMS AND ANIMAL PESTS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-10-04 | — | — | WO | disclosed |
| EP-0816379-A2 | DNA binding oligomers | BAYER AG (DE) | 1998-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10752977-B2 | Palladium separating agent, method for producing same and use of same | CCNA1, DDT, CCNE1 | SLC9A1 1198/4885KEAP1 1929/4885TSHR 3652/4885 |
| US-20100280244-A1 | PROCESS FOR PREPARING N-SUBSTITUTED HYDROXYPYRIMIDINONE CARBOXAMIDES | ALKBH3, DTYMK, DUT | SLC9A1 3879/4885KEAP1 4260/4885TSHR 4744/4885 |
| US-20160152607-A1 | MALEIC ACID DERIVATIVE, PRODUCTION METHOD FOR SAME, AND ANTI-CANCER COMPOSITION COMPRISING SAME | NR1H4, CBR1, NR1H2 | SLC9A1 939/4885KEAP1 1298/4885TSHR 1675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.