SCHEMBL3737216

SCHEMBL3737216

CSc1nnnn1CC(=O)O

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.60
KMT2A Q03164 2/20 0.60
NPC1 O15118 2/20 0.44
ALDH1A1 P00352 7/20 0.44
HPGD P15428 2/20 0.44
KDM4C Q9H3R0 1/20 0.42
MAPK1 P28482 2/20 0.41
GLA P06280 1/20 0.41
MAPT P10636 1/20 0.41
HTT P42858 2/20 0.38
POLB P06746 2/20 0.37
RAB9A P51151 2/20 0.36
HSD17B10 Q99714 1/20 0.36
TSHR P16473 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9087861 0.84 KMT2A (0.58) LMNAKMT2ANPC1ALDH1A1HPGD
SCHEMBL9331809 0.82 KMT2A (0.67) LMNAKMT2AALDH1A1HPGDMAPK1
SCHEMBL9994163 0.82 ALDH1A1 (0.49) LMNAKMT2ANPC1ALDH1A1HPGD
SCHEMBL3737213 0.81 ALDH1A1 (0.44) LMNAKMT2ANPC1ALDH1A1HPGD
SCHEMBL9088392 0.81 KMT2A (0.55) LMNAKMT2ANPC1ALDH1A1HPGD
SCHEMBL10769901 0.80 KMT2A (0.41) LMNAKMT2ANPC1ALDH1A1HPGD
SCHEMBL10403341 0.76 KMT2A (0.44) LMNAKMT2ANPC1ALDH1A1HPGD
SCHEMBL8316778 0.76 KMT2A (0.58) LMNAKMT2ANPC1ALDH1A1HPGD
SCHEMBL10403907 0.75 KMT2A (0.43) LMNAKMT2ANPC1ALDH1A1HPGD
SCHEMBL10403909 0.75 KMT2A (0.43) LMNAKMT2ANPC1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6420554-B1 REACTION OF BETA LACTAM WITH PHOSPHOROUS HALIDE IN THE PRESENCE OF BASE, ADDING PHENOL, REACTION WITH ALCOHOL AND REMOVAL OF ESTER OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 2002-07-16 US claimed
US-4547573-A BACTERICIDES ICI PHARMA (FR) 1985-10-15 US claimed
US-4504478-A Cephalosporin-1-oxide derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (FR) 1985-03-12 US claimed
US-4497949-A PHOTOTHERMOGRAPHY;COLOR FILMS;STORAGE STABILITY;ANTIFOGGING AGENTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-02-05 US claimed
US-4492692-A BACTERICIDE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-01-08 US claimed
US-4463173-A ANTIBIOTIC, BACTERICIDE ICI PHARMA (FR) 1984-07-31 US claimed
EP-0113965-A2 Process for the preparation of cephalosporin derivatives ICI PHARMA (FR) 1984-07-25 EP claimed
EP-0031708-B1 CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES THEREFOR ICI PHARMA (FR) 1984-06-13 EP claimed
EP-0075434-A2 Cephalosporins, their preparation and their pharmaceutical compositions ICI PHARMA (FR) 1983-03-30 EP claimed
EP-0072608-A2 Process for the preparation of cephalosporin derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-02-23 EP claimed
US-7825238-B2 Antiviral methods employing double esters of 2′, 3′-dideoxy-3′-fluoroguanosine MEDIVIR AB (SE) 2010-11-02 US disclosed
EP-1010701-B1 PROCESS FOR THE PREPARATION OF 3-CEPHEM COMPOUNDS OTSUKA KAGAKU KK (JP) 2008-01-16 EP disclosed
US-20070111980-A1 Process for preparing pure cephalosporine intermediates HETERO DRUGS LIMITED (IN) 2007-05-17 US disclosed
US-7186500-B2 Silver halide photographic lightsensitive material FUJI PHOTO FILM CO., LTD. (JP) 2007-03-06 US disclosed
US-7186500-B2 Silver halide photographic lightsensitive material FUJI PHOTO FILM CO., LTD. (JP) 2007-03-06 US disclosed
US-4251657-A Method for removing protective groups TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1981-02-17 US disclosed
US-4180571-A Arylmalonamido-1-oxadethiacephalosporins SHIONOGI & CO., LTD. (JP) 1979-12-25 US disclosed
EP-0003960-A1 6-Substituted thia-aza-compounds, their preparation and pharmaceutical compositions containing them CIBA-GEIGY AG (CH) 1979-09-19 EP disclosed
EP-0002586-A1 Method for removing a halogenoacetyl protective group from a halogenoacetyl amino compound Takeda Chemical Industries, Ltd. (JP) 1979-06-27 EP disclosed
US-4138486-A BACTERICIDES SHIONOGI & CO., LTD. (JP) 1979-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070111980-A1 Process for preparing pure cephalosporine intermediates ACMSD, CEL, MGAM LMNA 1502/4885KMT2A 690/4885NPC1 1598/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.