Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6472435 | 0.79 | ALDH1A1 (0.50) | CYP3A4HTTALDH1A1TSHRHSD17B10 | |
| SCHEMBL11778520 | 0.76 | CYP3A4 (0.42) | CYP3A4HTTALDH1A1TSHRHSD17B10 | |
| SCHEMBL1502420 | 0.75 | CYP3A4 (0.50) | CYP3A4HTTALDH1A1TSHRHSD17B10 | |
| SCHEMBL751119 | 0.75 | CYP3A4 (0.53) | CYP3A4HTTALDH1A1TSHRHSD17B10 | |
| SCHEMBL28003868 | 0.75 | CYP3A4 (0.53) | CYP3A4HTTALDH1A1TSHRHSD17B10 | |
| SCHEMBL5497977 | 0.74 | CYP3A4 (0.43) | CYP3A4HTTALDH1A1TSHRHSD17B10 | |
| SCHEMBL9879540 | 0.73 | CYP3A4 (0.45) | CYP3A4HTTALDH1A1TSHRHSD17B10 | |
| SCHEMBL11783872 | 0.73 | TSHR (0.47) | CYP3A4HTTALDH1A1TSHRHSD17B10 | |
| SCHEMBL10334775 | 0.73 | CYP3A4 (0.47) | CYP3A4HTTALDH1A1TSHRHSD17B10 | |
| SCHEMBL11498308 | 0.73 | CYP3A4 (0.47) | CYP3A4HTTALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7674943-B2 | Solid, hydrocarbon-insoluble, catalyst component containing magnesium, titanium, and halogen, and further contains an internal electron donor which does not contain a phthalate derivative, for example, ethyl (phenylacetoxy)acetate; stereospecific polymerization; highly crystalline propylene polymers | INEOS USA LLC (US) | 2010-03-09 | — | — | US | disclosed |
| US-7491781-B2 | Propylene polymer catalyst donor component | INEOS USA LLC (US) | 2009-02-17 | — | — | US | disclosed |
| US-20080214881-A1 | Propylene polymer catalyst donor component | INEOS USA LLC | 2008-09-04 | — | — | US | disclosed |
| US-20080207972-A1 | Propylene polymer catalyst donor component | INEOS USA LLC | 2008-08-28 | — | — | US | disclosed |
| US-20080194782-A1 | Propylene polymer catalyst donor component | INEOS USA LLC | 2008-08-14 | — | — | US | disclosed |
| EP-1863855-A2 | PROPYLENE POLYMER CATALYST DONOR COMPONENT | INEOS USA LLC (US) | 2007-12-12 | — | — | EP | disclosed |
| US-20070179047-A1 | Propylene polymer catalyst donor component | INNOVENE USA (US) | 2007-08-02 | — | — | US | disclosed |
| WO-2006096621-A2 | PROPYLENE POLYMER CATALYST DONOR COMPONENT | INNOVENE USA LLC (US) | 2006-09-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214881-A1 | Propylene polymer catalyst donor component | RAD52, NR2C2, PGR | CYP3A4 1427/4885HTT 1311/4885ALDH1A1 4642/4885 |
| US-20080207972-A1 | Propylene polymer catalyst donor component | RAD52, NR2C2, PGR | CYP3A4 1427/4885HTT 1311/4885ALDH1A1 4642/4885 |
| US-20080194782-A1 | Propylene polymer catalyst donor component | RAD52, NR2C2, PGR | CYP3A4 1427/4885HTT 1311/4885ALDH1A1 4642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.