Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.37 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7950557 | 0.84 | TDP1 (0.41) | TDP1L3MBTL1MITFCHIT1CHIA | |
| SCHEMBL6711052 | 0.84 | TDP1 (0.39) | TDP1L3MBTL1MITFCHIT1CHIA | |
| SCHEMBL9812322 | 0.83 | TDP1 (0.41) | TDP1L3MBTL1MITFCHIT1CHIA | |
| SCHEMBL2116076 | 0.82 | TDP1 (0.44) | TDP1L3MBTL1MITFCHIT1CHIA | |
| SCHEMBL5695790 | 0.82 | TDP1 (0.45) | TDP1L3MBTL1MITFCHIT1CHIA | |
| SCHEMBL5695792 | 0.82 | TDP1 (0.47) | TDP1L3MBTL1MITFCHIT1CHIA | |
| SCHEMBL28861068 | 0.75 | SLC6A2 (0.47) | TDP1L3MBTL1MITFCHIT1CHIA | |
| SCHEMBL8698275 | 0.74 | L3MBTL1 (0.39) | TDP1L3MBTL1MITFCHIT1CHIA | |
| SCHEMBL7771962 | 0.74 | CA1 (0.39) | TDP1L3MBTL1MITFCHIT1CHIA | |
| SCHEMBL8566033 | 0.73 | HRH3 (0.40) | CHIT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144610-A1 | PHARMACEUTICAL FORMULATIONS | SCHERING CORPORATION | 2010-06-10 | — | — | US | disclosed |
| US-6239277-B1 | ALKYLATION OF AMINE GROUP IN PIPERAZINE RING | SALSBURY CHEMICALS, INC. | 2001-05-29 | — | — | US | disclosed |