Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | CHIT1 | Q13231 | 2/20 | 0.41 |
| ▸ | CHIA | Q9BZP6 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | IDE | P14735 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5695790 | 0.87 | TDP1 (0.45) | TDP1L3MBTL1MITFCHIT1CHIA | |
| SCHEMBL2116076 | 0.85 | TDP1 (0.44) | TDP1L3MBTL1MITFCHIT1CHIA | |
| SCHEMBL28861068 | 0.82 | SLC6A2 (0.47) | TDP1L3MBTL1MITFCHIT1CHIA | |
| SCHEMBL9812322 | 0.82 | TDP1 (0.41) | TDP1L3MBTL1MITFCHIT1CHIA | |
| SCHEMBL3738377 | 0.82 | TDP1 (0.41) | TDP1L3MBTL1MITFCHIT1CHIA | |
| SCHEMBL7950557 | 0.81 | TDP1 (0.41) | TDP1L3MBTL1MITFCHIT1CHIA | |
| SCHEMBL7771962 | 0.79 | CA1 (0.39) | TDP1L3MBTL1MITFCHIT1CHIA | |
| SCHEMBL6711052 | 0.79 | TDP1 (0.39) | TDP1L3MBTL1MITFCHIT1CHIA | |
| SCHEMBL7775649 | 0.78 | CA1 (0.38) | TDP1L3MBTL1MITFCHIT1CHIA | |
| SCHEMBL8698275 | 0.77 | L3MBTL1 (0.39) | TDP1L3MBTL1MITFCHIT1CHIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222179-B1 | PROCESS FOR PREPARING PIPERAZINE-SUBSTITUTED ALIPHATIC CARBOXYLATES | CAMBREX CHARLES CITY INC (US) | 2006-06-21 | — | — | EP | disclosed |