Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | TEK | Q02763 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | CHIT1 | Q13231 | 2/20 | 0.38 |
| ▸ | CHIA | Q9BZP6 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711052 | 0.89 | TDP1 (0.39) | TDP1L3MBTL1MITFCHIT1CHIA | |
| SCHEMBL2116076 | 0.86 | TDP1 (0.44) | TDP1L3MBTL1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7115205 | 0.85 | HRH1 (0.42) | TDP1HRH1SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL5957371 | 0.84 | HRH1 (0.43) | TDP1HRH1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3738377 | 0.84 | TDP1 (0.41) | TDP1L3MBTL1MITFCHIT1CHIA | |
| SCHEMBL5695792 | 0.81 | TDP1 (0.47) | TDP1L3MBTL1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5695790 | 0.81 | TDP1 (0.45) | TDP1L3MBTL1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9812322 | 0.80 | TDP1 (0.41) | TDP1L3MBTL1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3738384 | 0.76 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3CHIT1CHIA | |
| SCHEMBL27629296 | 0.74 | TDP1 (0.51) | TDP1L3MBTL1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6239277-B1 | ALKYLATION OF AMINE GROUP IN PIPERAZINE RING | SALSBURY CHEMICALS, INC. | 2001-05-29 | — | — | US | disclosed |