Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.38 |
| ▸ | CHIT1 | Q13231 | 2/20 | 0.38 |
| ▸ | CHIA | Q9BZP6 | 2/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711048 | 0.90 | CHIT1 (0.36) | CHIT1CHIAMAPKAPK2SCN5ASCN2A | |
| SCHEMBL3738375 | 0.82 | PPARG (0.40) | SLC6A2SLC6A4SLC6A3CHIT1CHIA | |
| SCHEMBL5695787 | 0.81 | CHIT1 (0.41) | SLC6A2SLC6A4SLC6A3CHIT1CHIA | |
| Hydrochloric Acid SCHEMBL8697805 | 0.81 | PPARG (0.39) | SLC6A2SLC6A4SLC6A3CHIT1CHIA | |
| SCHEMBL8697920 | 0.79 | CHIT1 (0.37) | SLC6A2SLC6A4SLC6A3CHIT1CHIA | |
| SCHEMBL8691086 | 0.77 | MEN1 (0.40) | SLC6A2SLC6A4SLC6A3CA1CA2 | |
| SCHEMBL7950557 | 0.76 | TDP1 (0.41) | SLC6A2SLC6A4SLC6A3CHIT1CHIA | |
| SCHEMBL8698596 | 0.75 | CHIT1 (0.37) | SLC6A2SLC6A4SLC6A3CHIT1CHIA | |
| SCHEMBL2116076 | 0.74 | TDP1 (0.44) | SLC6A2SLC6A4SLC6A3CHIT1CHIA | |
| SCHEMBL8691089 | 0.73 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144610-A1 | PHARMACEUTICAL FORMULATIONS | SCHERING CORPORATION | 2010-06-10 | — | — | US | disclosed |
| US-6239277-B1 | ALKYLATION OF AMINE GROUP IN PIPERAZINE RING | SALSBURY CHEMICALS, INC. | 2001-05-29 | — | — | US | disclosed |