Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIT1 | Q13231 | 6/20 | 0.36 |
| ▸ | CHIA | Q9BZP6 | 4/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3738384 | 0.90 | SLC6A2 (0.38) | CHIT1CHIAMAPKAPK2SCN5ASCN2A | |
| SCHEMBL5695787 | 0.80 | CHIT1 (0.41) | CHIT1CHIAMAPKAPK2SCN5ASCN2A | |
| SCHEMBL6711052 | 0.78 | TDP1 (0.39) | CHIT1CHIASCN5ASCN2ASCN10A | |
| SCHEMBL3738375 | 0.78 | PPARG (0.40) | CHIT1CHIASCN5ASCN2ASCN10A | |
| SCHEMBL8691086 | 0.78 | MEN1 (0.40) | — | |
| SCHEMBL8697920 | 0.77 | CHIT1 (0.37) | CHIT1CHIASCN5ASCN2ASCN10A | |
| Hydrochloric Acid SCHEMBL8697805 | 0.77 | PPARG (0.39) | CHIT1CHIASCN5ASCN2ASCN10A | |
| SCHEMBL8697912 | 0.74 | CHIT1 (0.38) | CHIT1CHIASCN5ASCN2ASCN10A | |
| SCHEMBL8698596 | 0.73 | CHIT1 (0.37) | CHIT1CHIASCN5ASCN2ASCN10A | |
| SCHEMBL9812322 | 0.71 | TDP1 (0.41) | CHIT1CHIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040122023-A1 | Enantiomers of 1-[(4-chlorophenyl)phenylmethyl]-4-[(4-methylphenyl) sulfonyl] piperazine | COSSEMENT ERIC (BE) | 2004-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122023-A1 | Enantiomers of 1-[(4-chlorophenyl)phenylmethyl]-4-[(4-methylphenyl) sulfonyl] piperazine | RPLP1, QDPR, PRLHR | CHIT1 1346/4885CHIA 4665/4885MAPKAPK2 2295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.