Ethylene Glycol

Ethylene Glycol

SCHEMBL3738508

CCCOC(CC(=O)O)(CC(=O)O)C(=O)O.OCCO

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
LMNA P02545 2/20 0.36
CYP2D6 P10635 1/20 0.35
TSHR P16473 1/20 0.35
CYP2C19 P33261 1/20 0.35
HIF1A Q16665 1/20 0.35
HMGCR P04035 1/20 0.32
CHRM1 P11229 1/20 0.32
TBXA2R P21731 1/20 0.32
ADRA1A P35348 1/20 0.32
SLC13A5 Q86YT5 1/20 0.31
ACHE P22303 1/20 0.31
HSPD1 P10809 1/20 0.30
BLM P54132 1/20 0.30
HSPE1 P61604 1/20 0.30
FFAR3 O14843 1/20 0.30
HDAC3 O15379 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC8 Q9BY41 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9484651 0.94 CYP2C19 (0.39) ALDH1A1LMNACYP2D6TSHRCYP2C19
1,4-Butanediol SCHEMBL3739733 0.93 ACHE (0.37) ALDH1A1LMNACYP2D6TSHRCYP2C19
Di(Hydroxyethyl)Ether SCHEMBL3731298 0.91 TSHR (0.39) ALDH1A1LMNACYP2D6TSHRCYP2C19
Ethylene Glycol SCHEMBL3736370 0.89 TSHR (0.36) ALDH1A1LMNACYP2D6TSHRCYP2C19
Propylene Glycol SCHEMBL3731405 0.86 HSD17B10 (0.33) ALDH1A1LMNACYP2D6TSHRCYP2C19
SCHEMBL8427302 0.85 ALDH1A1 (0.36) ALDH1A1LMNACYP2D6TSHRCYP2C19
Ethylene Glycol SCHEMBL3734256 0.84 CYP2D6 (0.38) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
1,4-Butanediol SCHEMBL3731858 0.84 ACHE (0.39) ALDH1A1LMNATSHRACHE
SCHEMBL19863280 0.84 ALDH1A1 (0.37) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL1993032 0.82 ALDH1A1 (0.39) ALDH1A1LMNACYP2D6TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7825178-B2 Leveling agent for floor polish and aqueous floor polish composition DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2010-11-02 US disclosed
US-20070289481-A1 Leveling Agent for Floor Polish and Aqueous Floor Polish Composition DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2007-12-20 US disclosed